4-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester
- Product Name
- 4-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester
- CAS No.
- 933785-18-3
- Chemical Name
- 4-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester
- Synonyms
- Methyl 4-bromo-2-(trifluoromethoxy);2- trifluoromethoxy-4-bromobenzoate;Ethyl 4-bromo-2-(trifluoromethoxy)benzoate;4-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester;Benzoic acid, 4-bromo-2-(trifluoromethoxy)-, methyl ester
- CBNumber
- CB32470200
- Molecular Formula
- C9H6BrF3O3
- Formula Weight
- 299.04
- MOL File
- 933785-18-3.mol
4-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester Property
- Boiling point:
- 266℃
- Density
- 1.626
- Flash point:
- 115℃
- storage temp.
- Sealed in dry,Room Temperature
- form
- liquid
- color
- Clear, colourless
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M293840
- Product name
- Methyl4-Bromo-2-(trifluoromethoxy)benzoate
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- PC49082
- Product name
- Methyl4-bromo-2-(trifluoromethoxy)benzoate
- Packaging
- 5g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- PC49082
- Product name
- Methyl4-bromo-2-(trifluoromethoxy)benzoate
- Packaging
- 1g
- Price
- $34
- Updated
- 2021/12/16
- Product number
- 2623-B-14
- Product name
- Methyl 4-bromo-2-(trifluoromethoxy)benzoate
- Packaging
- 1g
- Price
- $72
- Updated
- 2021/12/16
- Product number
- 5836AC
- Product name
- Ethyl4-bromo-2-(trifluoromethoxy)benzoate
- Packaging
- 1g
- Price
- $91
- Updated
- 2021/12/16
4-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester Chemical Properties,Usage,Production
Synthesis
67-56-1
509142-48-7
933785-18-3
General procedure for the synthesis of methyl 4-bromo-2-(trifluoromethoxy)benzoate from methanol and 4-bromo-2-trifluoromethoxybenzoic acid: the compound 4-bromo-2-trifluoromethoxybenzoic acid (30.0 g, 0.11 mol) was suspended in a 4 M methanol-hydrochloric acid solution (500 mL), and the reaction was carried out at reflux overnight. After completion of the reaction, methanol was removed by distillation under reduced pressure. The resulting residue was extracted by partitioning with saturated sodium carbonate solution and ethyl acetate. The organic layer was dried with anhydrous sodium sulfate and concentrated under reduced pressure to afford the target product methyl 4-bromo-2-(trifluoromethoxy)benzoate (24.0 g, 77% yield).
References
[1] Patent: US2012/28952, 2012, A1. Location in patent: Page/Page column 19
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 16, p. 5979 - 6002
4-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Bromo-2-(trifluoromethoxy)benzoic acid methyl ester manufacturers
- Product
- Ethyl 4-bromo-2-(trifluoromethoxy)benzoate 933785-18-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-20