Ethyl 1-oxaspiro[2.5]octane-6-carboxylate

Product Name: Ethyl 1-oxaspiro[2.5]octane-6-carboxylate
CAS No.: 171361-65-2
Chemical Name: Ethyl 1-oxaspiro[2.5]octane-6-carboxylate
Synonyms: Ethyl 1-oxaspiro[2.5]octane-6-carboxylate;Ethyl 1-oxaspiro[2.5]octane-6-carboxylate 95+%;1-Oxaspiro[2.5]octane-6-carboxylic acid ethyl ester
CBNumber: CB32480591
Molecular Formula: C10H16O3
Formula Weight: 184.23
MOL File: 171361-65-2.mol

More

Less

Ethyl 1-oxaspiro[2.5]octane-6-carboxylate Property

Boiling point:: 257℃
Density: 1.10
Flash point:: 102℃
storage temp.: Inert atmosphere,Store in freezer, under -20°C

More

Less

Safety

HazardClass: IRRITANT
HS Code: 2932990090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: B441088
Product name: ethyl1-oxaspiro[2.5]octane-6-carboxylate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 046953
Product name: Ethyl 1-oxaspiro[2.5]octane-6-carboxylate
Purity: 92%
Packaging: 1g
Price: $145
Updated: 2021/12/16

Matrix Scientific

Product number: 046953
Product name: Ethyl 1-oxaspiro[2.5]octane-6-carboxylate
Purity: 92%
Packaging: 5g
Price: $450
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0392219
Product name: ETHYL-1-OXASPIRO[2.5]OCTANE-6-CARBOXYLATE
Purity: 95.00%
Packaging: 5MG
Price: $500.53
Updated: 2021/12/16

AK Scientific

Product number: 8814AA
Product name: Ethyl1-oxaspiro[2.5]octane-6-carboxylate
Packaging: 5g
Price: $652
Updated: 2021/12/16

More

Less

Ethyl 1-oxaspiro[2.5]octane-6-carboxylate Chemical Properties,Usage,Production

Synthesis

17159-79-4

1774-47-6

171361-65-2

General procedure for the synthesis of ethyl 1-oxaspiro[2.5]octane-6-carboxylate from ethyl 4-oxocyclohexanecarboxylate and trimethylsulfonium oxide iodide: Procedure 9a: To a mixture containing trimethylsulfonium oxide iodide (3.9 g, 11.76 mmol) and potassium tert-butoxide (cf. Synthetic Communications, 33(12), 2135-2143) was added ethyl 4-oxocyclohexanecarboxylate (1 g, 5.87 mmol, Aldrich) in a DMSO ( 20 ml) solution. The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the mixture was poured into water and extracted with ether. The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford ethyl 1-oxaspiro[2.5]octane-6-carboxylate (704.5 mg, 65% yield), which could be used in subsequent reactions without further purification. Another batch of compounds prepared by the same method showed the following NMR hydrogen spectral data: 1H NMR (400MHz, CDCl3): δ 4.06 (2H, q), 2.49-2.59 (2H, m), 2.26-2.28 (1H, m), 1.63-2.04 (6H, m), 1.27-1.49 (2H, m), 1.20 ( 3H, t), cis/trans isomer ratio 65:35.

References

[1] Patent: WO2008/92887, 2008, A1. Location in patent: Page/Page column 28
[2] Patent: WO2008/129007, 2008, A1. Location in patent: Page/Page column 32

Ethyl 1-oxaspiro[2.5]octane-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Ethyl 1-oxaspiro[2.5]octane-6-carboxylate Suppliers

China 17 United Kingdom 2 United States 5 Global 24

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Taizhou Elitechemie MediPharma Technology Co., Ltd.

Tel: 523-86810021 18921709486
Fax: gwli@elitechemie.com
Email: gwli@elitechemie.com
Country: China
ProdList: 504
Advantage: 65

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15393
Advantage: 58

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4969
Advantage: 58

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: 021-58958618
Email: sales@uhnshanghai.com
Country: China
ProdList: 1984
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15080
Advantage: 58

171361-65-2, Ethyl 1-oxaspiro[2.5]octane-6-carboxylateRelated Search:

1-Oxaspiro[2.5]octane-6-carboxylic acid ethyl ester

Ethyl 1-oxaspiro[2.5]octane-6-carboxylate

Ethyl 1-oxaspiro[2.5]octane-6-carboxylate 95+%

171361-65-2