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N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide

Product Name
N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide
CAS No.
67605-85-0
Chemical Name
N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide
Synonyms
C4AHL;C4-HSL;Ch-homoserinelactone;N-butyryl-L-Homoserine;Butyryl-L-hoMoserine lactone;N-butyryl-L-Homoserine lactone;N-[(3S)-2-oxooxolan-3-yl]butanamide;N-(2-oxotetrahydrofuran-3-yl)butanamide;(S)-N-(2-Oxotetrahydrofuran-3-yl)butyraMide;C4-HSL, N-Butyryl-L-hoMoserine lactone, PAI
CBNumber
CB32489923
Molecular Formula
C8H13NO3
Formula Weight
171.19
MOL File
67605-85-0.mol
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N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide Property

Melting point:
120-123 °C
Boiling point:
428.1±34.0 °C(Predicted)
Density 
1.13
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Solid
pka
14.78±0.20(Predicted)
color 
White to Off-White
Stability:
Stable under recommended storage conditions., Stable Under Recommended Storage C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3427
Product name
C4-HSL
Purity
≥95% (HPLC)
Packaging
10MG
Price
$79
Updated
2023/06/20
Sigma-Aldrich
Product number
SML3427
Product name
C4-HSL
Purity
≥95% (HPLC)
Packaging
50MG
Price
$255
Updated
2023/06/20
Cayman Chemical
Product number
10007898
Product name
N-butyryl-L-Homoserine lactone
Purity
≥95%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
10007898
Product name
N-butyryl-L-Homoserine lactone
Purity
≥95%
Packaging
10mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
10007898
Product name
N-butyryl-L-Homoserine lactone
Purity
≥95%
Packaging
25mg
Price
$116
Updated
2024/03/01
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N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide Chemical Properties,Usage,Production

Description

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homoserine lactone is a quorum-sensing signaling molecule produced by P. aeruginosa. It induces expression of the virulence genes lasB and rhlA in P. aeruginosa when used at a concentration of 10 μM. N-butyryl-L-Homoserine lactone (50 μM) induces rhamnolipid accumulation in P. aeruginosa growth media.

Uses

Butyryl-L-homoserine lactone is a short acylhomoserine lactone isolated from Pseudomonas aeruginosa in 1995 and demonstrated to be a quorum sensing modulator in biofilms. Acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorterchains displaying opposing actions to the longer chains.

Uses

N-butyryl-L-Homoserine lactone is a diffusable quorum sensing lactone.

Definition

ChEBI: (+)-a(S)-butyr-amido-r-butyrolactone is a N-acyl-amino acid.

N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide Suppliers

Qingdao Vochem Co., Ltd.
Tel
532-88066095 18661779210
Email
vochem@vochem.com
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China
ProdList
98
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60
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6854
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65
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17981
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Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
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15878
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Shanghai GL Peptide Ltd.
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+86-21-61263310; 13764994101 13764994101
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fisherwang@glschina.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
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021-65675885
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China
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Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
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0510-83583039
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willsun@peptide-search.com
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China
ProdList
6716
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 18892239720
Fax
010-60605840
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psaitong@jm-bio.com
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China
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12308
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Lynnchem
Tel
86-(0)29-85992781 17792393971
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info@lynnchem.com
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China
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67605-85-0, N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamideRelated Search:


  • N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide
  • N-butyryl-L-Homoserine lactone
  • Butyryl-L-hoMoserine lactone
  • C4-HSL, N-Butyryl-L-hoMoserine lactone, PAI
  • C4-HSL
  • N-butyryl-L-Homoserine
  • (S)-N-(2-Oxotetrahydrofuran-3-yl)butyraMide
  • N-(2-oxotetrahydrofuran-3-yl)butanamide
  • Ch-homoserinelactone
  • C4AHL
  • N-[(3S)-2-oxooxolan-3-yl]butanamide
  • Butanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
  • antibody-drug,antibacterial,ADC Linkers,Inhibitor,ADC,Bacterial,cleavable,biofilm,conjugates,Antibody-drug conjugates linkers,NButanoylLhomoserine lactone,inhibit,N Butanoyl L homoserine lactone
  • 67605-85-0