ChemicalBook > CAS DataBase List > Slv320

Slv320

Product Name
Slv320
CAS No.
251945-92-3
Chemical Name
Slv320
Synonyms
Slv320;SC-204288;Derenofylline;SLV320 >=98% (HPLC);SLV320; SLV-320; SLV 320; DERENOFYLLINE;4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;4-[(2-phenyl-7H-pyrrolo[2， 3-d]pyrimidin-4-yl)amino]cyclohexan-1-ol;(1R,4R)-4-(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol;trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;Cyclohexanol, 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans-
CBNumber
CB32492503
Molecular Formula
C18H20N4O
Formula Weight
308.38
MOL File
251945-92-3.mol
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Slv320 Property

Boiling point:
532.3±60.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Soluble to 100 mM in DMSO and to 50 mM in ethanol
form 
Powder
pka
15.15±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27666
Product name
Derenofylline
Packaging
5mg
Price
$92
Updated
2024/03/01
Cayman Chemical
Product number
27666
Product name
Derenofylline
Packaging
25mg
Price
$371
Updated
2024/03/01
Cayman Chemical
Product number
27666
Product name
Derenofylline
Packaging
1mg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
27666
Product name
Derenofylline
Packaging
10mg
Price
$166
Updated
2024/03/01
Tocris
Product number
3344
Product name
SLV320
Purity
≥99%(HPLC)
Packaging
10
Price
$181
Updated
2021/12/16
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Slv320 Chemical Properties,Usage,Production

Description

Derenofylline is an adenosine A1 receptor antagonist (Ki = 1 nM). It is selective for adenosine A1 over A2A, A2B, and A3 receptors (Kis = 398, 3,981, and 200 nM, respectively). It decreases adenosine A1 receptor-mediated adenosine-induced bradycardia in rats (ED50 = 0.49 mg/kg) but reduces A2 receptor-mediated adenosine-induced hypotension by only 44.6% when administered at an intravenous dose of 5 mg/kg. It prevents increases in heart levels of collagen I and III in nephrectomized rats when administered at a dose of 10 mg/kg per day. Derenofylline also reduces relative plaque counts in a Zika virus plaque-forming assay in A549 cells (IC50 = 58.6 nM) in an adenosine A1 receptor-independent manner without inducing cytotoxicity when used at concentrations less than 10 μM.

Uses

SLV 320 is an A1 antagonist.

Slv320 Preparation Products And Raw materials

Raw materials

Preparation Products

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Slv320 Suppliers

China 36 United Kingdom 1 United States 11 USA 1 Global 49
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
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022-23754520
Email
klq@cw-bio.com
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China
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Shanghai Chaolan Chemical Technology Center
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021-QQ：65489617 15618227136
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21-5161 9052
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Sales@ATKchemical.com
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China
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Jiangsu aikang biomedical research and development co., LTD
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025-66110311 13155353615
Email
qzhang@aikonchem.com
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China
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Career Henan Chemica Co
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+86-0371-86658258 +8613203830695
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0371-86658258
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laboratory@coreychem.com
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DC Chemicals
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021-58447131 13564518121
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sales@dcchemicals.com
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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Jingmo (Xiamen) Biotechnology Co., Ltd
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13621943973; 13621943973
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sales@jamxmpharmatech.com
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CONIER CHEM AND PHARMA LIMITED
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+8618523575427
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sales@conier.com
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Guangzhou Younan Technology Co., Ltd
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020-82000279 18988968278
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Shanghai Luofa Biochemical Technology Co., Ltd.
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Henan Weitesi Chemical Technology Co. LTD
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Energy Chemical
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cjbscvictory
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Jinan Jiuli Biotechnology Co. , Ltd.
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Beijing Jin Ming Biotechnology Co., Ltd.
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Bide Pharmatech Ltd.
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product02@bidepharm.com
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TargetMol Chemicals Inc.
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Beijing Solarbio Science & Tecnology Co., Ltd.
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Nanjing Tengyi Biotechnology Co., Ltd
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251945-92-3, Slv320Related Search:


  • Cyclohexanol, 4-((2-phenyl-1H-pyrrolo(2,3-D)pyrimidin-4-yl)amino)-, trans-
  • Slv320
  • trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol
  • (1R,4R)-4-(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol
  • SC-204288
  • Derenofylline
  • 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol
  • SLV320; SLV-320; SLV 320; DERENOFYLLINE
  • Cyclohexanol, 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans-
  • SLV320 >=98% (HPLC)
  • rel-(1r,4r)-4-((2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexan-1-ol
  • Inhibitor,P1 receptor,Derenofylline,Adenosine Receptor,SLV320,fibrosis,uraemic,SLV-320,cardiomyopathy,SLV 320,inhibit,Nephrectomy
  • 4-[(2-phenyl-7H-pyrrolo[2， 3-d]pyrimidin-4-yl)amino]cyclohexan-1-ol
  • 251945-92-3