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Brinzolamide-d5

Product Name
Brinzolamide-d5
CAS No.
1217651-02-9
Chemical Name
Brinzolamide-d5
Synonyms
Brinzolamide-d5;[2H5]-Brinzolamide
CBNumber
CB32507883
Molecular Formula
C12H21N3O5S3
Formula Weight
383.5
MOL File
1217651-02-9.mol
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Brinzolamide-d5 Property

storage temp. 
Refrigerator
solubility 
Ethanol
form 
Solid
color 
Crystalline
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Cayman Chemical
Product number
30006
Product name
Brinzolamide-d5
Packaging
500μg
Price
$279
Updated
2024/03/01
Cayman Chemical
Product number
30006
Product name
Brinzolamide-d5
Packaging
1mg
Price
$501
Updated
2024/03/01
TRC
Product number
B677602
Product name
Brinzolamide-d5
Packaging
5mg
Price
$1980
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
RDL0006690
Product name
BRINZOLAMIDE-D5
Purity
95.00%
Packaging
5MG
Price
$2783
Updated
2021/12/16
AK Scientific
Product number
7669DG
Product name
Brinzolamide-d5
Packaging
1mg
Price
$646
Updated
2021/12/16
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Brinzolamide-d5 Chemical Properties,Usage,Production

Description

Brinzolamide-d5 is intended for use as an internal standard for the quantification of brinzolamide by GC- or LC-MS. Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension. It also reduces intraocular pressure in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.

Chemical Properties

Crystalline Solid

Uses

Carbonic anhydrase inhibitor. Antiglaucoma agent.

Brinzolamide-d5 Preparation Products And Raw materials

Raw materials

Preparation Products

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Brinzolamide-d5 Suppliers

Canada 1 CHINA 13 India 4 United States 1 Global 19
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
Fax
QQ:2853117752
Email
3003392093@qq.com
Country
China
ProdList
7887
Advantage
55
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai isotope chemical co.,ltd
Tel
021-021-51600108 13062666369
Email
sales@chinaisotope.com
Country
China
ProdList
4272
Advantage
58

1217651-02-9, Brinzolamide-d5Related Search:

N-DESMETHYLDILTIAZEM, HYDROCHLORIDE DESACETYL DILTIAZEM HCL N-Desethyl Brinzolamide Diltiazem-d6 Diltiazem N-Oxide Brinzolamide Diltiazem Impurity 5 BrinzolaMide iMpurity Diltiazem impurity (S)-3,4-Dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide Diltiazem Impurity 4 Diltiazem hydrochloride Deacetyl Diltiazem N-Oxide N,N,O-Tridesmethyl Diltiazem Deacetyldiltiazem (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride Diltiazem Impurity 8 Diltiazem Impurity 3

  • [2H5]-Brinzolamide
  • Brinzolamide-d5
  • 1217651-02-9
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  • Isotope Labelled Compounds
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