Brinzolamide-d5

Product Name: Brinzolamide-d5
CAS No.: 1217651-02-9
Chemical Name: Brinzolamide-d5
Synonyms: Brinzolamide-d5;[2H5]-Brinzolamide
CBNumber: CB32507883
Molecular Formula: C12H21N3O5S3
Formula Weight: 383.5
MOL File: 1217651-02-9.mol

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Brinzolamide-d5 Property

storage temp.: Refrigerator
solubility: Ethanol
form: Solid
color: Crystalline

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 30006
Product name: Brinzolamide-d5
Packaging: 500μg
Price: $279
Updated: 2024/03/01

Cayman Chemical

Product number: 30006
Product name: Brinzolamide-d5
Packaging: 1mg
Price: $501
Updated: 2024/03/01

TRC

Product number: B677602
Product name: Brinzolamide-d5
Packaging: 5mg
Price: $1980
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: RDL0006690
Product name: BRINZOLAMIDE-D5
Purity: 95.00%
Packaging: 5MG
Price: $2783
Updated: 2021/12/16

AK Scientific

Product number: 7669DG
Product name: Brinzolamide-d5
Packaging: 1mg
Price: $646
Updated: 2021/12/16

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Brinzolamide-d5 Chemical Properties,Usage,Production

Description

Brinzolamide-d₅ is intended for use as an internal standard for the quantification of brinzolamide by GC- or LC-MS. Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC₅₀s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC₅₀ = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension. It also reduces intraocular pressure in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.

Chemical Properties

Crystalline Solid

Uses

Carbonic anhydrase inhibitor. Antiglaucoma agent.

Brinzolamide-d5 Preparation Products And Raw materials

Raw materials

Preparation Products

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Brinzolamide-d5 Suppliers

Canada 1 CHINA 15 India 4 United States 1 Global 21

Chemsky（shanghai）International Co.,Ltd.

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Shanghai EFE Biological Technology Co., Ltd.

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Hubei Yangxin Medical Technology Co., Ltd.

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Shanghai Hongye Biotechnology Co. Ltd

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Country: China
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Energy Chemical

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Shanghai isotope chemical co.,ltd

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Nanjing Shizhou Biology Technology Co.,Ltd

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Xiamen Research Biotechnology Co., Ltd.

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Shanghai Ziqi Biological Technology Co., Ltd.

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Shanghai Hao Biological Technology Co., Ltd.

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Shanghai Yubo Biotechnology Co., Ltd.

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Xiamen Huijia Biological Technology Co., Ltd.

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Shanghai Hao Zhun Biological Technology Co., Ltd.

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1217651-02-9, Brinzolamide-d5Related Search:

N-DESMETHYLDILTIAZEM, HYDROCHLORIDE DESACETYL DILTIAZEM HCL N-Desethyl Brinzolamide Diltiazem-d6 Diltiazem N-Oxide Brinzolamide Diltiazem Impurity 5 BrinzolaMide iMpurity Diltiazem impurity (S)-3,4-Dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide Diltiazem Impurity 4 Diltiazem hydrochloride Deacetyl Diltiazem N-Oxide N,N,O-Tridesmethyl Diltiazem Deacetyldiltiazem (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride Diltiazem Impurity 8 Diltiazem Impurity 3

[2H5]-Brinzolamide

Brinzolamide-d5

1217651-02-9

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