Methyl 2-(6-chloropyridin-3-yl)acetate
- Product Name
- Methyl 2-(6-chloropyridin-3-yl)acetate
- CAS No.
- 717106-69-9
- Chemical Name
- Methyl 2-(6-chloropyridin-3-yl)acetate
- Synonyms
- METHYL (6-CHLORO-3-PYRIDINYL)ACETATE;Methyl 2-(6-Chloro-3-pyridyl)acetate;Methyl 2-(6-chloropyridin-3-yl)acetate;6-Chloro-3-pyridineacetic acid methyl ester;2-Chloropyridine-5- acetic acidMethyl ester;3-Pyridineacetic acid, 6-chloro-, methyl ester;Methyl 2-(6-chloropyridin-3-yl)acetateACID AMIDE
- CBNumber
- CB32514168
- Molecular Formula
- C8H8ClNO2
- Formula Weight
- 185.61
- MOL File
- 717106-69-9.mol
Methyl 2-(6-chloropyridin-3-yl)acetate Property
- Boiling point:
- 133-135 °C(Press: 3 Torr)
- Density
- 1.259±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.40±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C8H8ClNO2/c1-12-8(11)4-6-2-3-7(9)10-5-6/h2-3,5H,4H2,1H3
- InChIKey
- NYAZLFKSCFNMKV-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=CC=C1CC(OC)=O
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M342290
- Product name
- Methyl2-(6-chloropyridin-3-yl)acetate
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- OR955786
- Product name
- Methyl2-(6-chloropyridin-3-yl)acetate
- Purity
- 98%
- Packaging
- 5g
- Price
- $108
- Updated
- 2021/12/16
- Product number
- OR955786
- Product name
- Methyl2-(6-chloropyridin-3-yl)acetate
- Purity
- 98%
- Packaging
- 10g
- Price
- $202
- Updated
- 2021/12/16
- Product number
- 126921
- Product name
- Methyl2-(6-chloropyridin-3-yl)acetate
- Purity
- >95%
- Packaging
- 1g
- Price
- $450
- Updated
- 2021/12/16
- Product number
- OR955786
- Product name
- Methyl2-(6-chloropyridin-3-yl)acetate
- Purity
- 98%
- Packaging
- 25g
- Price
- $492
- Updated
- 2021/12/16
Methyl 2-(6-chloropyridin-3-yl)acetate Chemical Properties,Usage,Production
Synthesis
67-56-1
39891-13-9
717106-69-9
Synthesis of compound 169.2. Concentrated sulfuric acid (1.9 mL) was slowly added to a solution of 2-chloropyridine-5-acetic acid (5.0 g, 29.23 mmol, 1.0 equiv) in methanol (50 mL) at room temperature. The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the mixture was poured into saturated sodium bicarbonate solution and extracted three times with ethyl acetate (EtOAc). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography to afford methyl 2-chloro-5-pyridylacetate (169.2, 5.0 g, 92.4% yield). MS (ES): m/z 185.4 [M + H]+.
References
[1] Patent: WO2015/131080, 2015, A1. Location in patent: Paragraph 00918; 00919
[2] Patent: US2016/251376, 2016, A1. Location in patent: Paragraph 0759; 0760; 0761
[3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004, vol. 43, # 4, p. 864 - 868
[4] Patent: WO2014/70979, 2014, A1. Location in patent: Page/Page column 23
[5] Patent: US2014/142081, 2014, A1. Location in patent: Paragraph 0872-0874
Methyl 2-(6-chloropyridin-3-yl)acetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 2-(6-chloropyridin-3-yl)acetate manufacturers
- Product
- Methyl 2-(6-chloropyridin-3-yl)acetateACID AMIDE 717106-69-9
- Price
- US $22.00-88.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2025-06-25
- Product
- Methyl 2-(6-chloropyridin-3-yl)acetate 717106-69-9
- Price
- US $150.00-1490.00/KG
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-25
- Product
- Methyl 2-(6-chloropyridin-3-yl)acetate 717106-69-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-14