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(2,3-dihydrobenzofuran-6-yl)methanol

Product Name
(2,3-dihydrobenzofuran-6-yl)methanol
CAS No.
1083168-69-7
Chemical Name
(2,3-dihydrobenzofuran-6-yl)methanol
Synonyms
4-Bromo-2,37-diaminopyridine;(2,3-Dihydrobenzofuran-6-yl);2,3-Dihydro-6-benzofuranmethanol;6-BenzofuranMethanol, 2,3-dihydro-;(2,3-dihydrobenzofuran-6-yl)methanol;2,3-dihydro-1-benzofuran-6-ylMethanol
CBNumber
CB32515978
Molecular Formula
C9H10O2
Formula Weight
150.17
MOL File
1083168-69-7.mol
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(2,3-dihydrobenzofuran-6-yl)methanol Property

Boiling point:
291.3±9.0 °C(Predicted)
Density 
1.217±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
14.31±0.10(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B426640
Product name
(2,3-Dihydrobenzofuran-6-yl)methanol
Packaging
10mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
5732AQ
Product name
2,3-dihydro-1-benzofuran-6-ylmethanol
Packaging
1g
Price
$1017.2
Updated
2021/12/16
Ambeed
Product number
A136197
Product name
(2,3-Dihydrobenzofuran-6-yl)methanol
Purity
98%
Packaging
100mg
Price
$186
Updated
2021/12/16
Abosyn
Product number
61-5132
Product name
(2,3-dihydrobenzofuran-6-yl)methanol
Purity
98%
Packaging
0.1g
Price
$220
Updated
2021/12/16
Ambeed
Product number
A136197
Product name
(2,3-Dihydrobenzofuran-6-yl)methanol
Purity
98%
Packaging
250mg
Price
$283
Updated
2021/12/16
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(2,3-dihydrobenzofuran-6-yl)methanol Chemical Properties,Usage,Production

Synthesis

1083168-68-6

1083168-69-7

Procedure: synthesis of (2,3-dihydrobenzofuran-6-yl)methanol; A THF solution of methyl 2,3-dihydrobenzofuran-6-carboxylate (17.8 g, 100 mmol) was slowly added to a stirred tetrahydrofuran (THF, 300 mL) solution of lithium aluminium hydride (6.1 g, 250 mmol) at 0 °C. The reaction mixture was continued to be stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction was quenched by careful addition of saturated aqueous sodium hydroxide solution, followed by extraction of the mixture with ethyl acetate. The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford (2,3-dihydrobenzofuran-6-yl)methanol (13.8 g, 92.0% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.17 (d, J = 7.2 Hz, 1H), 6.84 (d, J = 7.2 Hz, 1H), 6.81 (s, 1H), 4.62 (s, 2H), 4.58 (t, J = 8.4 Hz, 2H), 3.20 (t, J = 8.4 Hz, 2H), 1.67 ( br s, 1H).

References

[1] Patent: WO2008/141119, 2008, A2. Location in patent: Page/Page column 77; 79

(2,3-dihydrobenzofuran-6-yl)methanol Preparation Products And Raw materials

Raw materials

Preparation Products

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(2,3-dihydrobenzofuran-6-yl)methanol Suppliers

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