2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol

Product Name: 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol
CAS No.: 651030-55-6
Chemical Name: 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol
Synonyms: 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-ol;4-Hydroxyethylphenylboronic acid pinacol ester;4-(2-Hydroxyethyl)phenylboronic Acid Pinacol Ester;4-(2-Hydroxyethyl)benzeneboronic acid pinacol ester;2-[4-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]ETHANOL;2-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethan-1-ol;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneethanol;2-(4-(4,4,5,5-Tetramethyl-l.3,2-dioxaborolan-2-yl)phenyl)ethanol;Benzeneethanol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol
CBNumber: CB32516359
Molecular Formula: C14H21BO3
Formula Weight: 248.13
MOL File: 651030-55-6.mol

More

Less

2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol Property

Boiling point:: 363.2±25.0 °C(Predicted)
Density: 1.05±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 14.84±0.10(Predicted)
Appearance: White to off-white Solid

More

Less

Safety

HS Code: 2931900090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More

Less

N-Bromosuccinimide Price

TRC

Product number: T302853
Product name: 2-[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethan-1-ol
Packaging: 500mg
Price: $155
Updated: 2021/12/16

AK Scientific

Product number: AMTB1128
Product name: 2-(4-(4,4,5,5-Tetramethyl-l.3,2-dioxaborolan-2-yl)phenyl)ethanol
Packaging: 1g
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 130954
Product name: 2-[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethan-1-ol
Purity: >95%
Packaging: 1g
Price: $180
Updated: 2021/12/16

SynQuest Laboratories

Product number: 6660-1-87
Product name: 2-[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethan-1-ol
Packaging: 1g
Price: $221
Updated: 2021/12/16

AK Scientific

Product number: AMTB1128
Product name: 2-(4-(4,4,5,5-Tetramethyl-l.3,2-dioxaborolan-2-yl)phenyl)ethanol
Packaging: 5g
Price: $300
Updated: 2021/12/16

More

Less

2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol Chemical Properties,Usage,Production

Synthesis

4654-39-1

73183-34-3

651030-55-6

Step 1: Under nitrogen protection, 4-bromophenethyl alcohol (5.0 g, 25 mmol), pinacol ester of bisboronic acid (7.6 g, 30 mmol), potassium acetate (4.88 g, 49.7 mmol), and PdCl2 (dppf) (0.91 g, 1.2 mmol) were dissolved in 1,4-dioxane (100 mL). After purging the reaction mixture with nitrogen, it was stirred at 85°C for about 12 hours. After the reaction was completed, it was cooled to room temperature, diluted with water (100 mL) and extracted with EtOAc (2 x 100 mL). The organic layers were combined, washed with saturated aqueous NaCl (100 mL), dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by rapid chromatography on silica gel (17% EtOAc/petroleum ether). The target fraction was collected and concentrated under reduced pressure to give 2-(4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol (6.2 g, 100% yield). NMR (400MHz, CDCl3) δ 7.78 (d, J=7.9Hz, 2H), 7.29-7.23 (m, 2H), 3.87 (t, J=6.6Hz, 2H), 2.90 (t, J=6.6Hz, 2H), 1.36 (s, 12H).

References

[1] Patent: WO2016/168638, 2016, A1. Location in patent: Page/Page column 30; 31
[2] Patent: WO2016/168633, 2016, A1. Location in patent: Page/Page column 57
[3] Patent: WO2016/168641, 2016, A1. Location in patent: Page/Page column 105
[4] Journal of the American Chemical Society, 2014, vol. 136, # 42, p. 14742 - 14745
[5] Patent: EP1544194, 2005, A1. Location in patent: Page/Page column 37-38

2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol Suppliers

China 37 India 1 United Kingdom 1 United States 5 Global 44

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Shanghai ShiXian Chemical Technology Co., Ltd.

Tel: 18681884732
Fax: 021-51632502
Email: 2245256225@qq.com
Country: China
ProdList: 1728
Advantage: 50

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6874
Advantage: 55

Suzhou Chenke Biotech Co., Ltd.

Tel: 18662408853
Email: 2120408911@qq.com
Country: China
ProdList: 981
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Henan Alfachem Co.,Ltd.

Tel: 0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9988
Advantage: 58

Shanghai Puhao Chemical Technology Co. Ltd.

Tel: 13761817188
Email: 774028079@qq.com
Country: China
ProdList: 291
Advantage: 58

Shanghai Thunder Biological Technology Co., Ltd.

Tel: 18621609968
Email: 1162686636@qq.com
Country: China
ProdList: 876
Advantage: 58

651030-55-6, 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanolRelated Search:

Diethylzinc 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanol

2-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethan-1-ol

2-[4-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]ETHANOL

Benzeneethanol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-|||2-[4-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]ETHANOL

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneethanol

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-ol

4-Hydroxyethylphenylboronic acid pinacol ester

Benzeneethanol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

4-(2-Hydroxyethyl)phenylboronic Acid Pinacol Ester

2-(4-(4,4,5,5-Tetramethyl-l.3,2-dioxaborolan-2-yl)phenyl)ethanol

2-[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanol - [T57935]

4-(2-Hydroxyethyl)benzeneboronic acid pinacol ester

651030-55-6