6-AMINO-3,5-DINITROPYRIDINE
Preparation- Product Name
- 6-AMINO-3,5-DINITROPYRIDINE
- CAS No.
- 3073-30-1
- Chemical Name
- 6-AMINO-3,5-DINITROPYRIDINE
- Synonyms
- 3,5-Dinitro-2-pyridinamine;3,5-dinitropyridin-2-amine;6-AMINO-3,5-DINITROPYRIDINE;3,5-Dinitro-2-aminopyridine;2-AMINO-3,5-DINITROPYRIDINE;2-Pyridinamine,3,5-dinitro-;3,5-Dinitro-pyridin-2-ylaMine;2-Amino-3,5-dinitropyridine, 95%;6-AMINO-3,5-DINITROPYRIDINE ISO 9001：2015 REACH
- CBNumber
- CB3252361
- Molecular Formula
- C5H4N4O4
- Formula Weight
- 184.11
- MOL File
- 3073-30-1.mol
6-AMINO-3,5-DINITROPYRIDINE Property
- Melting point:
- 191-192 °C
- Boiling point:
- 403.1±40.0 °C(Predicted)
- Density
- 1.694±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- -1.68±0.49(Predicted)
Safety
- HazardClass
- IRRITANT-HARMFUL
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H341Suspected of causing genetic defects
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- FA146950
- Product name
- 2-Amino-3,5-dinitropyridine
- Packaging
- 5mg
- Price
- $66
- Updated
- 2021/12/16
- Product number
- FA146950
- Product name
- 2-Amino-3,5-dinitropyridine
- Packaging
- 10mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- Y8659
- Product name
- 3,5-Dinitropyridin-2-amine
- Packaging
- 2g
- Price
- $185
- Updated
- 2021/12/16
- Product number
- FA146950
- Product name
- 2-Amino-3,5-dinitropyridine
- Packaging
- 25mg
- Price
- $229
- Updated
- 2021/12/16
- Product number
- FA146950
- Product name
- 2-Amino-3,5-dinitropyridine
- Packaging
- 50mg
- Price
- $398
- Updated
- 2021/12/16
6-AMINO-3,5-DINITROPYRIDINE Chemical Properties,Usage,Production
Preparation
Ritter202 found that nitration of 2-amino-5-nitropyridine gave the 2-nitrarnino compound and further reaction gave 2-amino-3,5-dinitropyridine.
Uses
3,5-Dinitro-2-pyridinamine can be used to prepare antagonists for NMDA/glycine, AMPA, and Kainate Receptors.
Synthesis
2578-45-2
3073-30-1
The general procedure for the synthesis of 2-amino-3,5-dinitropyridine from 2-chloro-3,5-dinitropyridine was as follows: 2-chloro-3,5-dinitropyridine (22.3 g, 0.11 mol) was slowly added to a methanol solution of ammonia (7N, 150 mL) in batches at a low temperature of 5-10 °C. The reaction mixture was stirred continuously for 1 h at room temperature and subsequently poured into water (500 mL) to terminate the reaction. The resulting solid product was collected by filtration and washed with cold water (100 mL) to remove impurities. Finally, the product was dried to afford 2-amino-3,5-dinitropyridine (19.55 g, 97% yield), which was used directly in the subsequent reaction without further purification.
References
[1] Beilstein Journal of Organic Chemistry, 2017, vol. 13, p. 2854 - 2861
[2] Journal of Organic Chemistry, 1985, vol. 50, # 4, p. 484 - 487
[3] Journal of Medicinal Chemistry, 1997, vol. 40, # 22, p. 3679 - 3686
[4] Patent: WO2009/111277, 2009, A1. Location in patent: Page/Page column 53
[5] Patent: US2004/116466, 2004, A1
6-AMINO-3,5-DINITROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-AMINO-3,5-DINITROPYRIDINE manufacturers
- Product
- 6-AMINO-3,5-DINITROPYRIDINE 3073-30-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
- Product
- 6-AMINO-3,5-DINITROPYRIDINE 3073-30-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08