ChemicalBook > CAS DataBase List > RalfinaMide Mesylate

RalfinaMide Mesylate

Product Name: RalfinaMide Mesylate
CAS No.: 202825-45-4
Chemical Name: RalfinaMide Mesylate
Synonyms: CS-1138;RALFINAMIDE MESYLATE;FCE-26742A (mesylate);Ralfinamide mesylate, 10 mM in DMSO;(S)-2-((4-((2-fluorobenzyl)oxy)benzyl)aMino)propanaMide Methanesulfonate;(S)-2-((4-((2-fluorobenzyl)oxy)benzyl)amino)propanamide methanesulfonic acid;(2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate;FCE-26742A,Na channels,Na+ channels,Ralfinamide mesylate,Sodium Channel,Ralfinamide,inhibit,Inhibitor
CBNumber: CB32538283
Molecular Formula: C18H23FN2O5S
Formula Weight: 398.4490232
MOL File: 202825-45-4.mol

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RalfinaMide Mesylate Property

Melting point:: 230-235°C
storage temp.: 2-8°C
solubility: H2O: >15mg/mL
form: powder
color: white to beige
optical activity: [α]/D 10 to 15° (c=1 HOAc)
Water Solubility: H2O: >15mg/mL

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0378
Product name: Ralfinamide mesylate
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $133
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0378
Product name: Ralfinamide mesylate
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $353
Updated: 2025/07/31

Tocris

Product number: 4029
Product name: Ralfinamide mesylate
Purity: ≥99%(HPLC)
Packaging: 10
Price: $136
Updated: 2021/12/16

Tocris

Product number: 4029
Product name: Ralfinamide mesylate
Purity: ≥99%(HPLC)
Packaging: 50
Price: $572
Updated: 2021/12/16

Usbiological

Product number: 256427
Product name: Ralfinamide mesylate
Packaging: 10mg
Price: $423
Updated: 2021/12/16

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RalfinaMide Mesylate Chemical Properties,Usage,Production

Uses

Ralfinamide mesylate is a mixed sodium and N-type calcium channel protein inhibitor. Inhibitory activity of Ralfinamide mesylate is voltage dependent, with higher potency towards inactivated channels. Ralfinamide mesylate is useful in preventing, alleviating and curing a wide range of pathologies, including pain, migraine, peripheral diseases, cardiovascular diseases, inflammatory processes affecting all body systems, disorders affecting skin and related tissues, disorders of the respiratory system, disorders of the immune and endocrinol. systems, gastrointestinal, urogenital, metabolic and seizure disorders.

Biological Activity

Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependent, with higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents.

in vivo

Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain^[1].

Animal Model:	81 adult male Sprague–Dawley male rats (260–460 g)^[1]
Dosage:	80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)
Administration:	Oral gavage; twice daily; until postoperative day 42
Result:	Suppressed neuropathic pain.

RalfinaMide Mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from RalfinaMide Mesylate manufacturers

Career Henan Chemical Co

Product: RalfinaMide Mesylate 202825-45-4
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-13

202825-45-4, RalfinaMide MesylateRelated Search:

RALFINAMIDE MESYLATE

(S)-2-((4-((2-fluorobenzyl)oxy)benzyl)aMino)propanaMide Methanesulfonate

CS-1138

(2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate

FCE-26742A (mesylate)

(S)-2-((4-((2-fluorobenzyl)oxy)benzyl)amino)propanamide methanesulfonic acid

FCE-26742A,Na channels,Na+ channels,Ralfinamide mesylate,Sodium Channel,Ralfinamide,inhibit,Inhibitor

Ralfinamide mesylate, 10 mM in DMSO

202825-45-4

C17H19FN2O2CH3SO3H