5-chloro-4-iodo-2-nitroaniline
- Product Name
- 5-chloro-4-iodo-2-nitroaniline
- CAS No.
- 335349-57-0
- Chemical Name
- 5-chloro-4-iodo-2-nitroaniline
- Synonyms
- 5-chloro-4-iodo-2-nitroaniline;5-Chloro-4-iodo-2-nitrophenylamine;5-chloro-4-iodo-2-nitrobenzenaMine;Benzenamine, 5-chloro-4-iodo-2-nitro-
- CBNumber
- CB32545942
- Molecular Formula
- C6H4ClIN2O2
- Formula Weight
- 298.47
- MOL File
- 335349-57-0.mol
5-chloro-4-iodo-2-nitroaniline Property
- Boiling point:
- 389.7±42.0 °C(Predicted)
- Density
- 2.169
- storage temp.
- 2-8°C(protect from light)
- pka
- -2.43±0.25(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2921420090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- C380638
- Product name
- 5-Chloro-4-iodo-2-nitro-phenylamine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C380638
- Product name
- 5-Chloro-4-iodo-2-nitro-phenylamine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- C380638
- Product name
- 5-Chloro-4-iodo-2-nitro-phenylamine
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CS-0060133
- Product name
- 5-Chloro-4-iodo-2-nitroaniline
- Purity
- 97.01%
- Packaging
- 5g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- CS-0060133
- Product name
- 5-Chloro-4-iodo-2-nitroaniline
- Purity
- 97.01%
- Packaging
- 1g
- Price
- $33
- Updated
- 2021/12/16
5-chloro-4-iodo-2-nitroaniline Chemical Properties,Usage,Production
Synthesis
1635-61-6
335349-57-0
The general procedure for the synthesis of 5-chloro-4-iodo-2-nitroaniline from 2-nitro-5-chloroaniline was as follows: first, a 50 mL round-bottomed flask was prepared and purged with nitrogen to maintain an inert atmosphere. To the flask was added 5-chloro-2-nitroaniline (10 g, 57.95 mmol, 1.00 eq.), acetic acid (100 mL) and N-iodosuccinimide (NIS, 13 g, 57.78 mmol, 1.00 eq.). The reaction mixture was stirred in an oil bath at 50 °C for 3 hours. Upon completion of the reaction, the mixture was poured into 300 mL of water and the resulting solid was collected by filtration. Subsequently, the solid was washed with 200 mL of saturated sodium bicarbonate solution and three times 200 mL of water. Ultimately, 17 g (88% yield) of 5-chloro-4-iodo-2-nitroaniline was obtained as a yellow solid.
References
[1] Synlett, 2008, # 10, p. 1467 - 1470
[2] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 24, p. 6811 - 6815
[3] MedChemComm, 2013, vol. 4, # 7, p. 1118 - 1123
[4] Patent: US2013/281392, 2013, A1. Location in patent: Paragraph 0148; 0150; 0151
[5] Patent: CN106496037, 2017, A. Location in patent: Paragraph 0026-0028
5-chloro-4-iodo-2-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
5-chloro-4-iodo-2-nitroaniline Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 5-chloro-4-iodo-2-nitroaniline manufacturers
- Product
- 5-chloro-4-iodo-2-nitroaniline 335349-57-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-07
- Product
- 5-chloro-4-iodo-2-nitroaniline 335349-57-0
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 10000MT
- Release date
- 2023-08-17