Z-NH-5(ethylene glycol)-acetic acid

Product Name: Z-NH-5(ethylene glycol)-acetic acid
CAS No.: 1449390-66-2
Chemical Name: Z-NH-5(ethylene glycol)-acetic acid
Synonyms: CbzNH-P5-CH2CO2H;Z-NH-PEG5-CH2COOH;CBZ-NH-PEG5-CH2COOH;CBZ-NH-PEG5-acetic acid;Z-NH-5(ethylene glycol)-acetic acid;3-Oxo-1-phenyl-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid;5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH
CBNumber: CB32547012
Molecular Formula: C20H31NO9
Formula Weight: 429.46
MOL File: 1449390-66-2.mol

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Z-NH-5(ethylene glycol)-acetic acid Property

storage temp.: Store at -20 °C
Appearance: colorless liquid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS107905
Product name: CbzNH-PEG5-CH2COOH
Purity: 97%
Packaging: 250mg
Price: $283
Updated: 2021/12/16

chempep

Product number: 280303
Product name: Z-NH-PEG5-CH2COOH
Purity: >=95%
Packaging: 1g
Price: $433
Updated: 2021/12/16

ChemPep

Product number: 280303
Product name: Z-NH-PEG5-CH2COOH
Packaging: 5g
Price: $1083
Updated: 2021/12/16

Acrotein

Product number: B-1093
Product name: CbzNH-PEG5-CH2COOH
Purity: 97%
Packaging: 1g
Price: $412.5
Updated: 2021/12/16

purepeg

Product number: 4322905
Product name: CBZ-NH-PEG5-CH2COOH
Purity: min.97%
Packaging: 1g
Price: $450
Updated: 2021/12/16

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Z-NH-5(ethylene glycol)-acetic acid Chemical Properties,Usage,Production

Uses

Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Z-NH-5(ethylene glycol)-acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-NH-5(ethylene glycol)-acetic acid Suppliers

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1449390-66-2, Z-NH-5(ethylene glycol)-acetic acidRelated Search:

CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA Z-NH-PEG8-CH2CH2COOH Z-12-aMino-4,7,10-trioxadodecanoic acid Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid Z-NH-PEG10-CH2CH2COOH Z-21-aMino-4,7,10,13,16,19-hexaoxaheneicosanoic acid Z-8-aMino-3,6-dioxaoctanoic acid Z-9-aMino-4,7-dioxanonanoic acid Z-NH-8(ethylene glycol)-acetic acid Z-18-aMino-4,7,10,13,16-pentaoxaoctadecanoic acid Z-NH-PEG12-CH2CH2COOH

Z-NH-5(ethylene glycol)-acetic acid

Z-NH-PEG5-CH2COOH

CBZ-NH-PEG5-acetic acid

CBZ-NH-PEG5-CH2COOH

5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester

CbzNH-P5-CH2CO2H

inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH

CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester

3-Oxo-1-phenyl-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid

1449390-66-2

PEGylated Amino Acid