Z-NH-5(ethylene glycol)-acetic acid

Product Name: Z-NH-5(ethylene glycol)-acetic acid
CAS No.: 1449390-66-2
Chemical Name: Z-NH-5(ethylene glycol)-acetic acid
Synonyms: CbzNH-P5-CH2CO2H;Z-NH-PEG5-CH2COOH;CBZ-NH-PEG5-CH2COOH;CBZ-NH-PEG5-acetic acid;Z-NH-5(ethylene glycol)-acetic acid;5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH
CBNumber: CB32547012
Molecular Formula: C20H31NO9
Formula Weight: 429.46
MOL File: 1449390-66-2.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS107905
Product name: CbzNH-PEG5-CH2COOH
Purity: 97%
Packaging: 250mg
Price: $283
Updated: 2021/12/16

chempep

Product number: 280303
Product name: Z-NH-PEG5-CH2COOH
Purity: >=95%
Packaging: 1g
Price: $433
Updated: 2021/12/16

ChemPep

Product number: 280303
Product name: Z-NH-PEG5-CH2COOH
Packaging: 5g
Price: $1083
Updated: 2021/12/16

Acrotein

Product number: B-1093
Product name: CbzNH-PEG5-CH2COOH
Purity: 97%
Packaging: 1g
Price: $412.5
Updated: 2021/12/16

purepeg

Product number: 4322905
Product name: CBZ-NH-PEG5-CH2COOH
Purity: min.97%
Packaging: 1g
Price: $450
Updated: 2021/12/16

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Z-NH-5(ethylene glycol)-acetic acid Chemical Properties,Usage,Production

Biological Activity

Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Z-NH-5(ethylene glycol)-acetic acid Preparation Products And Raw materials

Raw materials

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1449390-66-2, Z-NH-5(ethylene glycol)-acetic acidRelated Search:

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Z-NH-5(ethylene glycol)-acetic acid

Z-NH-PEG5-CH2COOH

CBZ-NH-PEG5-acetic acid

CBZ-NH-PEG5-CH2COOH

5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester

CbzNH-P5-CH2CO2H

inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH

CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester

1449390-66-2

PEGylated Amino Acid