Erteberel (LY500307)

Product Name: Erteberel (LY500307)
CAS No.: 533884-09-2
Chemical Name: Erteberel (LY500307)
Synonyms: Erteberel;Phenchlobenpyrrone;CS-897;SERBA-1;LY500307;LY500307 (Erteberel);Erteberel (LY500307);Erteberel LY500307 LY-500307;Erteberel (LY500307) USP/EP/BP;Inhibitor,LY-500307,inhibit,Estrogen Receptor/ERR,Erteberel,LY 500307
CBNumber: CB32561485
Molecular Formula: C18H18O3
Formula Weight: 282.33
MOL File: 533884-09-2.mol

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Erteberel (LY500307) Property

Boiling point:: 485.2±45.0 °C(Predicted)
Density: 1.268
storage temp.: Store at -20°C
solubility: insoluble in H2O; ≥14.1 mg/mL in DMSO; ≥48.3 mg/mL in EtOH
form: solid
pka: 9.79±0.30(Predicted)
color: Off-white to light brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22130
Product name: Erteberel
Purity: ≥98%
Packaging: 1mg
Price: $72
Updated: 2024/03/01

Cayman Chemical

Product number: 22130
Product name: Erteberel
Purity: ≥98%
Packaging: 5mg
Price: $301
Updated: 2024/03/01

Cayman Chemical

Product number: 22130
Product name: Erteberel
Purity: ≥98%
Packaging: 10mg
Price: $530
Updated: 2024/03/01

TRC

Product number: E649895
Product name: Erteberel
Packaging: 1mg
Price: $195
Updated: 2021/12/16

ApexBio Technology

Product number: B1518
Product name: Erteberel(LY500307)
Packaging: 5mg
Price: $350
Updated: 2021/12/16

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Erteberel (LY500307) Chemical Properties,Usage,Production

Uses

Erteberel is a highly selective estrogen receptor β (ERβ) agonist.

Biological Activity

erteberel (ly500307) is a potent and selective erβ (estrogen receptor beta) agonist (ec50 = 0.66 nm). [1]estrogen receptors are nuclear hormone receptors that act as a ligand-activated transcription factor. it regulates gene expression, cell proliferation and differentiation in target tissues and involved in breast cancer, endometrial cancer and osteoporosis etc. [1]in transcription assay of cotransfected human prostate cancer cell line, erteberel showed potency (ec50 = 0.66 nm), selectivity (32-fold) and full agonist function (>90% relative efficacy) to erβ than to erα. [1]in mouse model, prostate wet weight of cd-1 mice were measured following oral daily doses of erteberel for 7 days. results showed reduction on prostate weight in a dose-dependent manner (0.01 mg/kg – 0.05 mg/kg), and no effect on testes/seminal vesicle weight and androgens testosterone/dihydrotestosterone circulating level. [1]

References

[1] norman bh, dodge ja, richardson ti, borromeo ps, lugar cw, jones sa, chen k, wang y, durst gl, barr rj, montrose-rafizadeh c, osborne he, amos rm, guo s, boodhoo a, krishnan v. benzopyrans are selective estrogen receptor beta agonists with novel activity in models of benign prostatic hyperplasia. j med chem. 2006 oct 19;49(21):6155-7.

Erteberel (LY500307) Preparation Products And Raw materials

Raw materials

Preparation Products

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Erteberel (LY500307) Suppliers

China 69 United States 12 Global 81

Shanghai Boyle Chemical Co., Ltd.

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JinYan Chemicals(ShangHai) Co.,Ltd.

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NCE Biomedical Co.,Ltd.

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GIHI CHEMICALS CO.,LTD

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ShangHai Caerulum Pharma Discovery Co., Ltd.

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Shanghai JONLN Reagent Co., Ltd.

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Suzhou yacoo science co.,Ltd

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View Lastest Price from Erteberel (LY500307) manufacturers

Henan Fengda Chemical Co., Ltd

Product: Erteberel (LY500307) 533884-09-2
Price: US $32.00-1.30/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

Career Henan Chemical Co

Product: Erteberel (LY500307) 533884-09-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-13

Career Henan Chemical Co

Product: Erteberel (LY500307) 533884-09-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-13

533884-09-2, Erteberel (LY500307)Related Search:

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LY500307 (Erteberel)

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Erteberel (LY500307)

Phenchlobenpyrrone

CS-897

SERBA-1

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Erteberel (LY500307) USP/EP/BP

Erteberel LY500307 LY-500307

Inhibitor,LY-500307,inhibit,Estrogen Receptor/ERR,Erteberel,LY 500307

533884-09-2

Inhibitors