4-(2-hydroxypropan-2-yl)phenylboronic acid

Product Name: 4-(2-hydroxypropan-2-yl)phenylboronic acid
CAS No.: 886593-45-9
Chemical Name: 4-(2-hydroxypropan-2-yl)phenylboronic acid
Synonyms: 4-(2-Hydroxy-2-propanyl)phenylboronic Acid;4-(2-hydroxypropan-2-yl)phenylboronic acid;B-[4-(1-hydroxy-isopropyl)phenyl]boronic acid;[4-(1-Hydroxy-1-methylethyl)phenyl]boronic acid;B-[4-(1-Hydroxy-1-methylethyl)phenyl]boronic acid;4-(2-hydroxypropan-2-yl)phenylboronic acid, 96%min;Boronic acid, B-[4-(1-hydroxy-1-methylethyl)phenyl]-;(4-(2-Hydroxypropan-2-yl)phenyl)boronic acid(contains varying amounts of Anhydride)
CBNumber: CB32604957
Molecular Formula: C9H13BO3
Formula Weight: 180.01
MOL File: 886593-45-9.mol

More

Less

4-(2-hydroxypropan-2-yl)phenylboronic acid Property

Boiling point:: 354.4±44.0 °C(Predicted)
Density: 1.16±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 8.66±0.17(Predicted)
Appearance: White to off-white Solid

More

Less

Safety

HS Code: 2931900090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TRC

Product number: H961885
Product name: 4-(2-Hydroxypropan-2-yl)phenylboronicacid
Packaging: 250mg
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-W006341
Product name: (4-(2-Hydroxypropan-2-yl)phenyl)boronicacid
Purity: 97.03%
Packaging: 1g
Price: $110
Updated: 2021/12/16

AK Scientific

Product number: V8689
Product name: 4-(2-Hydroxypropan-2-yl)phenylboronicacid
Packaging: 1g
Price: $244
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BOR0005663
Product name: (4-(2-HYDROXYPROPAN-2-YL)PHENYL)BORONIC ACID
Purity: 95.00%
Packaging: 1G
Price: $401.1
Updated: 2021/12/16

ChemScene

Product number: CS-W006341
Product name: (4-(2-Hydroxypropan-2-yl)phenyl)boronicacid
Purity: 97.03%
Packaging: 250mg
Price: $45
Updated: 2021/12/16

More

Less

4-(2-hydroxypropan-2-yl)phenylboronic acid Chemical Properties,Usage,Production

Synthesis

5419-55-6

2077-19-2

886593-45-9

General procedure for the synthesis of 4-(2-hydroxypropan-2-yl)phenylboronic acid from triisopropyl borate and 2-hydroxy-2-(4-bromophenyl)propane: 1. n-BuLi (2.5 M hexane solution, 1.00 mL, 2.5 mmol) was slowly added dropwise to a THF (20 mL) solution of 2-hydroxy-2-(4-bromophenyl)propane (0.50 g, 2.33 mmol) at -78 °C. 2. After 1.5 hours of reaction, n-BuLi (0.95 mL, 2.38 mmol) was added and stirring was continued at -78 °C for 2 hours. 3. triisopropyl borate (1.08 mL, 4.66 mmol) was added and the reaction mixture was slowly warmed to room temperature and stirred for 3 days. 4. Upon completion of the reaction, the reaction was quenched by the addition of 1N HCl and extracted with EtOAc 3 times. 5. The organic phases were combined, washed with brine, dried over anhydrous MgSO4 and concentrated under reduced pressure to give 0.29 g of crude product. 6. purified by column chromatography, first eluted with 50% EtOAc/hexane, then eluted with 10% MeOH/EtOAc to obtain partially purified product. 7. Final grinding with ether gave 51 mg (13% yield) of the target product 4-(2-hydroxypropan-2-yl)phenylboronic acid (PP33) as a white solid. NMR data (MeOH-d4): δ 7.67 (d, J = 8.3 Hz, 1H), 7.54 (d, J = 7.88 Hz, 1H), 7.45-7.40 (m, 2H), 1.97 (s, 6H).

References

[1] Patent: WO2006/48727, 2006, A1. Location in patent: Page/Page column 75-76

4-(2-hydroxypropan-2-yl)phenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-(2-hydroxypropan-2-yl)phenylboronic acid Suppliers

China 79 India 3 United Kingdom 1 United States 7 Global 90

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
Advantage: 55

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Youd Chemical Technology Co., Ltd.

Tel: 021-37910092; 15821801668
Fax: 021-37910267
Email: cong44@126.com
Country: China
ProdList: 293
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

AllyChem Co., Ltd.

Tel: 0411-62313318 13942603642
Fax: 0411-87549748
Email: info@allychem.com
Country: China
ProdList: 1028
Advantage: 65

More

Less

View Lastest Price from 4-(2-hydroxypropan-2-yl)phenylboronic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 4-(2-hydroxypropan-2-yl)phenylboronic acid 886593-45-9
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-07-03

Career Henan Chemical Co

Product: 4-(2-hydroxypropan-2-yl)phenylboronic acid 886593-45-9
Price: US $2.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: ask
Release date: 2020-01-08

886593-45-9, 4-(2-hydroxypropan-2-yl)phenylboronic acidRelated Search:

3-CHLORO-5-METHOXYBENZENEBORONIC ACID 2-METHOXY-6-METHYLPYRIDINE-3-BORONIC ACID 2-CHLORO-6-FLUORO-3-METHYLPHENYLBORONIC& 2-ETHOXY-6-METHYL-3-PYRIDINYLBORONIC ACID 1-(3-Chlorophenyl)pyrazole-4-boronic acid 2-METHOXY-4-(TRIFLUOROMETHYL)-PHENYLBORONIC ACID 4-(tert-Butyldimethylsilyloxy)-3-methoxyphenylboronic acid 2,3-Difluoro-5-methylphenylboronic acid [4-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl]boronic acid 2-Fluoro-4-methylphenylboronic acid Trihydroxymethylpropane 2,2-bis(4-hydroxyphenyl)propane

4-(2-hydroxypropan-2-yl)phenylboronic acid

4-(2-Hydroxy-2-propanyl)phenylboronic Acid

B-[4-(1-hydroxy-isopropyl)phenyl]boronic acid

[4-(1-Hydroxy-1-methylethyl)phenyl]boronic acid

Boronic acid, B-[4-(1-hydroxy-1-methylethyl)phenyl]-

B-[4-(1-Hydroxy-1-methylethyl)phenyl]boronic acid

(4-(2-Hydroxypropan-2-yl)phenyl)boronic acid(contains varying amounts of Anhydride)

4-(2-hydroxypropan-2-yl)phenylboronic acid, 96%min

886593-45-9