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Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester

Product Name
Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester
CAS No.
99552-78-0
Chemical Name
Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester
Synonyms
Methyl α-bromo-2-methoxybenzeneacetate;Methyl 2-broMo-2-(2-Methoxyphenyl)acetate;Methyl alpha-bromo-2-methoxy-benzeneacetate;bromo-(2-methoxyphenyl)acetic acid methyl ester;Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester;Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester;Benzeneacetic acid, alpha-broMo-2-Methoxy-, Methyl ester
CBNumber
CB32614642
Molecular Formula
C10H11BrO3
Formula Weight
259.1
MOL File
99552-78-0.mol
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Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester Property

storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0369147
Product name
METHYL-2-BROMO-2-(2-METHOXYPHENYL)ACETATE
Purity
95.00%
Packaging
5G
Price
$135.45
Updated
2021/12/16
Chemenu
Product number
CM126615
Product name
methyl2-bromo-2-(2-methoxyphenyl)acetate
Purity
95%
Packaging
1g
Price
$204
Updated
2021/12/16
Ambeed
Product number
A864000
Product name
Methyl2-bromo-2-(2-methoxyphenyl)acetate
Purity
95+%
Packaging
1g
Price
$240
Updated
2021/12/16
Crysdot
Product number
CD12000200
Product name
Methyl2-bromo-2-(2-methoxyphenyl)acetate
Purity
95+%
Packaging
5g
Price
$594
Updated
2021/12/16
Ambeed
Product number
A864000
Product name
Methyl2-bromo-2-(2-methoxyphenyl)acetate
Purity
95+%
Packaging
5g
Price
$717
Updated
2021/12/16
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Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester Chemical Properties,Usage,Production

Synthesis

27798-60-3

99552-78-0

General procedure for the synthesis of 2-bromo-2-(2-methoxyphenyl)acetic acid methyl ester from 2-(2-methoxyphenyl)acetic acid: 14.6 g (81.2 mmol) of 2-(2-methoxyphenyl)acetic acid methyl ester, 15.2 g (85.3 mmol) of N-bromosuccinimide, and the catalytic amount of AIBN were dissolved in 180 mL of CTC, and the mixture was heated and stirred under refluxing The mixture was heated and stirred under reflux conditions for 2 hours. After completion of the reaction, the reaction solution was cooled and filtered, followed by removal of the solvent under vacuum. 21.6 g (100% yield) of yellow oily product was obtained. The product was characterized by 1H-NMR (CDCl3): δ 3.78 (s, 3H), 3.87 (s, 3H), 5.90 (s, 1H), 6.88 (d, J=8.31 Hz, 1H), 6.99 (t, J=7.5 Hz, 1H), 7.32 (dt, J=7.6 Hz, 1.5 Hz, 1H), 7.61 (dd, J=7.6 Hz, 1.5 Hz, 1.5 Hz), 7.61 (dd, J=7.6 Hz, 1.5 Hz). 7.6 Hz, 1.5 Hz, 1H). Mass spectrum (API-ES, pos) m/z = 259 [M + H]+.

References

[1] Patent: WO2008/25736, 2008, A1. Location in patent: Page/Page column 63
[2] Patent: WO2007/139992, 2007, A2. Location in patent: Page/Page column 59

Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl ester Suppliers

Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69

99552-78-0, Benzeneacetic acid, α-broMo-2-Methoxy-, Methyl esterRelated Search:


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  • bromo-(2-methoxyphenyl)acetic acid methyl ester
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  • Methyl alpha-bromo-2-methoxy-benzeneacetate
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