AH3960

Product Name: AH3960
CAS No.: 862907-48-0
Chemical Name: AH3960
Synonyms: AH3960;AH-3960 (AH 3960;1,3-Dibutyl-5-(diaminomethylene)pyrimidine-2,4,6-trione;1,3-dibutyl-5-(diaminomethylidene)-1,3-diazinane-2,4,6-trione;2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dibutyl-5-(diaminomethylene)-
CBNumber: CB32627303
Molecular Formula: C13H22N4O3
Formula Weight: 282.34
MOL File: 862907-48-0.mol

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AH3960 Property

form: Solid
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: INB0001431
Product name: AH-3960
Purity: 95.00%
Packaging: 5MG
Price: $502.72
Updated: 2021/12/16

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AH3960 Chemical Properties,Usage,Production

Description

AH-3960 is an agonist of thyroid hormone receptor-1 (PTHR1).

Uses

AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1)[1][2].

References

[1] Yamamoto S, et al. Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists. Bioorg Med Chem. 2012 Apr 1;20(7):2338-52. DOI:10.1016/j.bmc.2012.02.005
[2] Carter PH, et al. Actions of the small molecule ligands SW106 and AH-3960 on the type-1 parathyroid hormone receptor. Mol Endocrinol. 2015 Feb;29(2):307-21. DOI:10.1210/me.2014-1129

AH3960 Preparation Products And Raw materials

Raw materials

Preparation Products

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AH3960 Suppliers

China 25 United States 3 Global 28

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862907-48-0, AH3960Related Search:

AH3960

1,3-dibutyl-5-(diaminomethylidene)-1,3-diazinane-2,4,6-trione

AH-3960 (AH 3960

2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dibutyl-5-(diaminomethylene)-

1,3-Dibutyl-5-(diaminomethylene)pyrimidine-2,4,6-trione

862907-48-0