ChemicalBook > CAS DataBase List > AMG 487

AMG 487

Product Name
AMG 487
CAS No.
473719-41-4
Chemical Name
AMG 487
Synonyms
AMG 487;N-[(1R)-1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide;(R)-N-(1-(3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(pyridin-3-ylmethyl)-2-(4-(trifluoromethoxy)phenyl)acetamide;Benzeneacetamide, N-[(1R)-1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-;Metastatic,metastasis,inhibit,cancer,CXCL11,CXC chemokine receptors,AMG-487,AMG487,CXCL10,chemokine,receptor,CXCR3,AMG 487,CXCR,Inhibitor,Breast,colon
CBNumber
CB32627318
Molecular Formula
C32H28F3N5O4
Formula Weight
603.59
MOL File
473719-41-4.mol
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AMG 487 Property

Melting point:
161.2℃ (ethyl acetate heptane )
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO:41.0(Max Conc. mg/mL);67.93(Max Conc. mM)
form 
A crystalline solid
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3153
Product name
AMG 487
Purity
≥98% (HPLC)
Packaging
10MG
Price
$89
Updated
2024/03/01
Sigma-Aldrich
Product number
SML3153
Product name
AMG 487
Purity
≥98% (HPLC)
Packaging
50MG
Price
$358
Updated
2024/03/01
Cayman Chemical
Product number
28416
Product name
AMG 487
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
28416
Product name
AMG 487
Packaging
25mg
Price
$684
Updated
2024/03/01
Cayman Chemical
Product number
28416
Product name
AMG 487
Packaging
5mg
Price
$179
Updated
2024/03/01
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AMG 487 Chemical Properties,Usage,Production

Uses

N-[(1R)-1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide is a selective and potent antagonist of the chemokine receptor CXCR3.

AMG 487 Preparation Products And Raw materials

Raw materials

Preparation Products

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AMG 487 Suppliers

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473719-41-4, AMG 487Related Search:


  • AMG 487
  • N-[(1R)-1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide
  • Benzeneacetamide, N-[(1R)-1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-
  • (R)-N-(1-(3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(pyridin-3-ylmethyl)-2-(4-(trifluoromethoxy)phenyl)acetamide
  • Metastatic,metastasis,inhibit,cancer,CXCL11,CXC chemokine receptors,AMG-487,AMG487,CXCL10,chemokine,receptor,CXCR3,AMG 487,CXCR,Inhibitor,Breast,colon
  • 473719-41-4
  • C32H28F3N5O4