EC-17

Product Name: EC-17
CAS No.: 583037-91-6
Chemical Name: EC-17
Synonyms: EC-17;FTIC-Folate;Folate-FTIC;EC-17 free acid;LMEBZGHLPGBLSU-PMERELPUSA-N;L-Glutamine, N2-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-N-[2-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]ethyl]-
CBNumber: CB32658187
Molecular Formula: C42H36N10O10S
Formula Weight: 872.86
MOL File: 583037-91-6.mol

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EC-17 Property

Density: 1.67±0.1 g/cm3(Predicted)
pka: 3.57±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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EC-17 Chemical Properties,Usage,Production

Uses

Folate-FITC (EC-17) is a folic acid derivative that binds to fluorescein isothiocyanate (FITC) to give it fluorescent labeling properties. Folate-fitc is used to induce the formation of pseudo-immunological synapses between anti-FITC CAR T cells and target cells expressing Folate receptors (FRα or FRβ). Folate-FITC can be used to develop controlled CAR-T cell therapies for research in non-small cell lung cancer (NSCLC)[1].

References

[1] Chu W, et al. Bi-specific ligand-controlled chimeric antigen receptor T-cell therapy for non-small cell lung cancer[J]. BioScience trends, 2018, 12(3): 298-308. DOI:10.5582/bst.2018.01048

EC-17 Preparation Products And Raw materials

Raw materials

Preparation Products

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EC-17 Suppliers

China 7 United States 3 Global 10

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai Biopharmaleader Co., Ltd.

Tel: +86 18721201413
Fax: +86 (21) 5775-8967
Email: sales@biopharmaleader.com
Country: China
ProdList: 1720
Advantage: 58

Beijing xinyanhui pharmaceutical research and development co., LTD

Tel: 13969155946
Email: 1461866103@qq.com
Country: China
ProdList: 16111
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

583037-91-6, EC-17Related Search:

EC-17

LMEBZGHLPGBLSU-PMERELPUSA-N

L-Glutamine, N2-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-N-[2-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]ethyl]-

EC-17 free acid

Folate-FTIC

FTIC-Folate

583037-91-6

C42H36N10O10S