ChemicalBook > CAS DataBase List > 6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine

6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine

Product Name
6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine
CAS No.
1337523-99-5
Chemical Name
6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine
Synonyms
6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine;6-Bromo-1,2,3,4-tetrahydro-phthalen-1-ylamine;1-Naphthalenamine, 6-bromo-1,2,3,4-tetrahydro-;6-Bromo-1,2,3,4-tetrahydro-naphthalen-1-ylamine;6-BROMO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE-HCL
CBNumber
CB32662779
Molecular Formula
C10H12BrN
Formula Weight
226.11
MOL File
1337523-99-5.mol
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6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine Property

Boiling point:
300.0±42.0 °C(Predicted)
Density 
1.413±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
9.19±0.20(Predicted)
Appearance
Yellow to brown Liquid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B681128
Product name
6-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
B681128
Product name
6-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine
Packaging
50mg
Price
$110
Updated
2021/12/16
TRC
Product number
B681128
Product name
6-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine
Packaging
100mg
Price
$155
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0367656
Product name
6-BROMO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE
Purity
95.00%
Packaging
5MG
Price
$497.4
Updated
2021/12/16
Ambeed
Product number
A209042
Product name
6-Bromo-1,2,3,4-tetrahydronaphthalen-1-amine
Purity
95%
Packaging
100mg
Price
$49
Updated
2021/12/16
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6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine Chemical Properties,Usage,Production

Synthesis

66361-67-9

1337523-99-5

6-Bromo-3,4-dihydronaphthalen-1(2H)-one (9.5 g, 42.2 mmol) was used as raw material and suspended in 2-propanol (250 mL). Subsequently, sodium cyanoborohydride (NaBH3CN, 13.3 g, 211 mmol) and ammonium acetate (65.1 g, 844 mmol) were added sequentially. The reaction mixture was stirred at room temperature for 4 hours before heating to reflux and continuing to stir for 22 hours. Upon completion of the reaction, the mixture was cooled to room temperature, poured into ice water (500 mL) and the pH was adjusted with sodium hydroxide solution to >10. The mixture was extracted with dichloromethane (CH2Cl2, 2 x 25 mL), the organic layers were combined and dried with anhydrous magnesium sulfate (MgSO4). After filtration, the crude product (9.842 g) was obtained by vacuum concentration. Purification by fast chromatography (silica gel, 100 g, eluent 2% to 10% dichloromethane solution in methanol) afforded the target compound 6-bromo-1,2,3,4-tetrahydronaphthalen-1-amine (8.08 g, 85% yield) as a light red oil. The mass spectrum (MS) showed [M+H]+ m/z 226.0 (with IBr isotope).

References

[1] Patent: WO2012/101011, 2012, A2. Location in patent: Page/Page column 49
[2] Patent: US2013/18055, 2013, A1. Location in patent: Paragraph 0305-0306
[3] Patent: WO2015/89327, 2015, A1

6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine Suppliers

China 42 India 1 United States 5 Global 48
Alchem Pharmtech,Inc.
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United States
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Synthonix Inc
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Combi-Blocks Inc.
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SynChem，Inc
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Matrix Scientific
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United States
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View Lastest Price from 6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
6-Bromo-1,2,3,4-tetrahydronaphthalen-1-amine 1337523-99-5
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-07-30
Career Henan Chemical Co
Product
6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMine 1337523-99-5
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

1337523-99-5, 6-BroMo-1,2,3,4-tetrahydronaphthalen-1-aMineRelated Search:

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