ChemicalBook > CAS DataBase List > CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester

CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester

Product Name
CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester
CAS No.
247068-82-2
Chemical Name
CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester
Synonyms
Boc-L-leucine epoxyketone;EOS-60549;CFE-4B (Carfilzomib);PR171 intermedaite I;Boc-leucine-epoxyketone;ert-Butyl ((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopen;[(1S)-3-Methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]carb...;N-Boc-2(S)-Amino-4-methyl-1-[(2R)-methyl-oxiranyl]-pentan-1-one;[(1S)-3-Methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]carbamic;tert-butyl 4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-ylcarbamate
CBNumber
CB32665457
Molecular Formula
C14H25NO4
Formula Weight
271.35
MOL File
247068-82-2.mol
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CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester Property

Boiling point:
369.8±37.0 °C(Predicted)
Density 
1.061±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
11.08±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B809210
Product name
tert-Butyl((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate
Packaging
500mg
Price
$1045
Updated
2021/12/16
AK Scientific
Product number
6856DN
Product name
Tert-butyl((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate
Packaging
100mg
Price
$1701
Updated
2021/12/16
AK Scientific
Product number
6856DN
Product name
Tert-butyl((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate
Packaging
500mg
Price
$1807
Updated
2021/12/16
ChemScene
Product number
CS-M2423
Product name
tert-Butyl((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate
Purity
99.78%
Packaging
250mg
Price
$69
Updated
2021/12/16
ChemScene
Product number
CS-M2423
Product name
tert-Butyl((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate
Purity
99.78%
Packaging
1g
Price
$171
Updated
2021/12/16
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CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester Chemical Properties,Usage,Production

Uses

tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.

CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester Suppliers

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View Lastest Price from CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester manufacturers

Changzhou Rokechem Technology Co., Ltd.
Product
tert-Butyl ((s)-4-methyl-1-((r)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate 247068-82-2
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
97%
Supply Ability
1-10000kgs
Release date
2023-06-12
Career Henan Chemical Co
Product
Boc-L-leucine epoxyketone 247068-82-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1000KG
Release date
2019-09-04

247068-82-2, CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl esterRelated Search:


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  • tert-butyl 4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-ylcarbamate
  • tert-butyl N-[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]carbamate
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  • ert-Butyl ((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopen
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  • [(1S)-3-Methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]carb...
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  • CarbaMic acid,N-[ (1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxira-nyl]carbony1] -, 1,1-diMethyl ethy1 ester
  • 247068-82-2