ChemicalBook > CAS DataBase List > 1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product Name
1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS No.
1238702-58-3
Chemical Name
1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Synonyms
1-Phenyl-1H-pyrazole-5-boronic Acid Pinacol Ester;(1-PHENYL-1H-PYRAZOL-5-YL)BORONIC ACID PINACOL ESTER;1-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole;1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1H-Pyrazole, 1-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber
CB32666111
Molecular Formula
C15H19BN2O2
Formula Weight
270.13
MOL File
1238702-58-3.mol
More
Less

1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
Light yellow to yellow Solid
More
Less

Safety

HS Code 
2933199090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
P399930
Product name
1-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Packaging
10mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
4531AA
Product name
1-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Packaging
250mg
Price
$246
Updated
2021/12/16
Apolloscientific
Product number
OR471708
Product name
1-Phenyl-1H-pyrazole-5-boronicacidpinacolester
Purity
97%
Packaging
250mg
Price
$435
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BOR0006061
Product name
1-PHENYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE
Purity
95.00%
Packaging
5MG
Price
$500.4
Updated
2021/12/16
AK Scientific
Product number
4531AA
Product name
1-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Packaging
1g
Price
$537
Updated
2021/12/16
More
Less

1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Chemical Properties,Usage,Production

Synthesis

76-09-5

1238702-56-1

1238702-58-3

The general procedure for the synthesis of 1-phenyl-pyrazole-5-boronic acid pinacol ester from pinacol and the compound (CAS: 1238702-56-1) is as follows: with reference to Example 132, a mixture of 1-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole and 1-phenyl-1H-pyrazole-5-boronic acid was room temperature was dissolved in toluene (86 mL). Subsequently, pinacol (5.39 g, 45.6 mmol) and boric acid (8.57 g, 45.6 mmol) were added. The reaction mixture was heated to 40 °C and the reaction was stirred at this temperature for 2 days. After completion of the reaction, the mixture was concentrated under reduced pressure and the residue was ground with hexane to afford pinacol ester of 1-phenyl-pyrazole-5-boronic acid (7.93 g, 64% yield) as a light yellow solid. The product was characterized by 1H NMR (DMSO-d6, 300 MHz): δ 1.23 (12H, s), 6.84 (1H, s), 7.34-7.59 (5H, m), 7.75 (1H, d, J = 1.9 Hz).

References

[1] Patent: US2010/197651, 2010, A1. Location in patent: Page/Page column 73-74
[2] Patent: US2013/150344, 2013, A1. Location in patent: Paragraph 0586; 0587
[3] Patent: US2013/137700, 2013, A1. Location in patent: Paragraph 0449; 0450
[4] Patent: US2013/137675, 2013, A1. Location in patent: Paragraph 0673; 0674

1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Suppliers

China 43 India 1 United States 3 Global 47
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai ShiXian Chemical Technology Co., Ltd.
Tel
18681884732
Fax
021-51632502
Email
2245256225@qq.com
Country
China
ProdList
1728
Advantage
50
Changsha Luxing Bio-Chem Technology Co., Ltd.
Tel
0731-88827538 15873153880
Fax
0731-88827238
Email
luxingbc@126.com
Country
China
ProdList
1995
Advantage
65
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
Shanghai Rong Lin Medical Technology Co., Ltd.
Tel
18602194589
Email
lincy-110@163.com
Country
China
ProdList
863
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
9998
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
qqyang@aikonchem.com
Country
China
ProdList
15814
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
14948
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000 13917643586;
Email
admin@jingshipharmatech.com
Country
China
ProdList
9856
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Hunan chemfish Scientific co.,ltd
Tel
19313119705 15707487186
Email
sales@chemfish.com
Country
China
ProdList
4960
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Shanghai Lanle Bird Industrial Co., Ltd.
Tel
15021845385
Email
765325601@qq.com
Country
China
ProdList
3609
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Shanghai Yihua Chemical Co., Ltd.
Tel
021-6785342
Fax
QQ:2771325243 Inquiry
Email
2771325243@qq.com
Country
China
ProdList
271
Advantage
58
Zhengzhou Alpha Chemical Co. LTD
Tel
0371-0371-53732842 13383863444
Fax
QQ：3002612166
Email
3002612166@qq.com
Country
China
ProdList
9996
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
29668
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39665
Advantage
58
Hubei Hannuo Pharmaceutical Technology Co., Ltd
Tel
18662190603
Email
437347250@qq.com
Country
China
ProdList
7325
Advantage
58
AAB-PHARMA LIMITED
Tel
02566880956
Email
3325708371@qq.com
Country
China
ProdList
7869
Advantage
58
Anhui Henuo Biotechnology Co., Ltd
Tel
18455579438
Country
China
ProdList
16684
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
Zhuhai Aobokai Biomedical Technology Co., Ltd.
Tel
400-0628126 18736790110;
Email
sales-team@aobchem.com.cn
Country
China
ProdList
50000
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
syeu@accelachem.com
Country
China
ProdList
11015
Advantage
58
Shaanxi Xihua Chemical Industry Co., Ltd
Tel
029-81136151 17392212881
Email
1095@dideu.com
Country
China
ProdList
10001
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Shanghai Yaoheping Biopharmaceutical Technology Co., Ltd
Tel
021-57540919 13120888836
Email
lily@yhp-biomedicine.com
Country
China
ProdList
8089
Advantage
58
Shanghai Scochem Technology Co., Ltd
Tel
+86-021-33758897 +86-13701882790
Email
sales@scochem.com
Country
China
ProdList
1977
Advantage
58
Coresyn Pharmatech Co., Ltd.
Tel
+86-571-86626709 +86-18157142896
Email
cbc@coresyn.com
Country
China
ProdList
9984
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58

1238702-58-3, 1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleRelated Search:

2-(3-Fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(3-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol 2-(4-(Bromomethyl)-2-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(2-CHLORO-3-METHOXYPHENYL)-4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLANE 4-Chloro-2-methylphenylboronic acid pinacol ester 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 2-Cyano-4-(trifluoromethyl)phenylboronic acid pinacol ester

  • 1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
  • 1-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
  • (1-PHENYL-1H-PYRAZOL-5-YL)BORONIC ACID PINACOL ESTER
  • 1-Phenyl-1H-pyrazole-5-boronic Acid Pinacol Ester
  • 1H-Pyrazole, 1-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
  • 1238702-58-3