360 A iodide

Product Name: 360 A iodide
CAS No.: 737763-37-0
Chemical Name: 360 A iodide
Synonyms: 360 A iodide;360A (iodide);3,3'-[2,6-Pyridinediylbis(carbonylimino)]bis[1-methylquinolinium] diiodide
CBNumber: CB32666580
Molecular Formula: C27H23IN5O2+
Formula Weight: 576.42
MOL File: 737763-37-0.mol

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360 A iodide Property

storage temp.: Store at -20°C
solubility: insoluble in H2O; insoluble in EtOH; insoluble in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: A3120
Product name: 360Aiodide
Packaging: 5mg
Price: $230
Updated: 2021/12/16

ChemScene

Product number: CS-1560
Product name: 360Aiodide
Purity: ≥98.0%
Packaging: 5mg
Price: $240
Updated: 2021/12/16

ApexBio Technology

Product number: A3120
Product name: 360Aiodide
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-1560
Product name: 360Aiodide
Purity: ≥98.0%
Packaging: 10mg
Price: $384
Updated: 2021/12/16

ApexBio Technology

Product number: A3120
Product name: 360Aiodide
Packaging: 25mg
Price: $650
Updated: 2021/12/16

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360 A iodide Chemical Properties,Usage,Production

Biological Activity

360a is a 2,6-pyridine-dicarboxamide derivative displaying strong affinity and selectivity for g-quadruplex structures and selective telomerase inhibition in vitro assays. 360a is a g-quadruplex ligand, which can influence the consequence of g-quadruplex formation and/or stabilization.

in vitro

we found a s-phase accumulation in atm-proficient, but not in atm-deficient ebv-lymphocytes treated with 360a before induction of cell death. however, atm status did not modify cell cycle distribution in 360a-treated sv40-fibroblasts and hela cells compared to dmso treated controls [1]. dna-pkcs-dependent nhej was responsible for sister telomere fusions as a direct consequence of g-quadruplex formation and/or stabilization induced by 360a on parental telomere g strands. nhej and hr activation at telomeres altered mitotic progression in treated cells [2]. this compound was shown to display a potent affinity and selectivity for telomeric g-quadruplex dna over duplex dna and to induce delayed growth inhibition in ht1080 tumor cell line [3].

360 A iodide Preparation Products And Raw materials

Raw materials

Preparation Products

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360 A iodide Suppliers

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737763-37-0, 360 A iodideRelated Search:

MPP+ IODIDE DiR iodide [1,1‘-dioctadecyl-3,3,3',3‘-tetramethylindotricarbocyanine iodide] 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide

360 A iodide

360A (iodide)

3,3'-[2,6-Pyridinediylbis(carbonylimino)]bis[1-methylquinolinium] diiodide

737763-37-0

C27H23I2N5O2

C27H23N5O22I