1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-

Product Name: 1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-
CAS No.: 1294504-67-8
Chemical Name: 1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-
Synonyms: Tezacaftor Intermediate;(2R)-1-{5-amino-2-[1-(benzyloxy)-2-methylpropan-2-yl]-6-fluo...;(2R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-o;(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol;(2R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol;(R)-1-(5-aMino-2-(1-(benzyloxy)-2-Methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol;(2R)-1-[5-amino-6-fluoro-2-(2-methyl-1-phenylmethoxypropan-2-yl)indol-1-yl]-3-phenylmethoxypropan-2-ol;(2R)-1-{5-amino-2-[1-(benzyloxy)-2-methyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol;1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-;1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-
CBNumber: CB32667956
Molecular Formula: C29H33FN2O3
Formula Weight: 476.58
MOL File: 1294504-67-8.mol

More

Less

1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)- Property

Boiling point:: 648.5±55.0 °C(Predicted)
Density: 1.16±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: DMSO (Slightly), Methanol (Very Slightly)
form: Solid
pka: 13.99±0.20(Predicted)
color: Very Dark Grey
InChIKey: RABRVTLWYYBNAK-FKEMPHOKNA-N
SMILES: C(N1C2=C(C=C(N)C(F)=C2)C=C1C(C)(C)COCC1=CC=CC=C1)[C@@H](O)COCC1=CC=CC=C1 |&1:24,r|

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

warning

Hazard statements

H302Harmful if swallowed

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: A619483
Product name: (R)-1-(5-Amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol
Packaging: 10mg
Price: $1400
Updated: 2021/12/16

Matrix Scientific

Product number: 122022
Product name: (2R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol
Purity: 97.0%
Packaging: 1g
Price: $4752
Updated: 2021/12/16

AK Scientific

Product number: 2909AH
Product name: (R)-1-(5-Amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol
Packaging: 1g
Price: $6465
Updated: 2021/12/16

ChemScene

Product number: CS-M2463
Product name: 1H-Indole-1-ethanol,5-amino-2-[1,1-dimethyl-2-(phenylmethoxy)ethyl]-6-fluoro-α-[(phenylmethoxy)methyl]-,(αR)-
Packaging: 250mg
Price: $500
Updated: 2021/12/16

ChemScene

Product number: CS-M2463
Product name: 1H-Indole-1-ethanol,5-amino-2-[1,1-dimethyl-2-(phenylmethoxy)ethyl]-6-fluoro-α-[(phenylmethoxy)methyl]-,(αR)-
Packaging: 100mg
Price: $300
Updated: 2021/12/16

More

Less

1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)- Chemical Properties,Usage,Production

Uses

(R)-1-(5-Amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol is a Tezacaftor (T321510) intermediate. Tezacaftor is used as a combination therapy with Ivacaftor for the treatment of patients with cystic fibrosis.

1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)- Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)- Suppliers

China 66 India 3 United Kingdom 1 United States 5 Global 75

ShangHai Onsyn-Chemical Technology Co., Ltd.

Tel: 13917628136 15900795984
Fax: +86-21-58359326
Email: 572350448@qq.com
Country: China
ProdList: 255
Advantage: 55

Suzhou Joubedii Pharmaceutical Technology Co., Ltd.

Tel: 15162465251
Email: huangcs@jobetterpharm.com
Country: China
ProdList: 17
Advantage: 58

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7440
Advantage: 65

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 26716
Advantage: 65

Chem-Stone Co.,Ltd.

Tel: 020-82185713,82185709 13418171485
Fax: 020-82185696
Email: sales@chem-stone.com
Country: China
ProdList: 744
Advantage: 56

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3505
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39999
Advantage: 60

BEIJING EAGLE SKY PHARMATECH CO., LTD

Tel: 010-88755821 13911359480
Email: sophia_818@126.com
Country: China
ProdList: 300
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

More

Less

View Lastest Price from 1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)- manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)- 1294504-67-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-22

1294504-67-8, 1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-Related Search:

2-tirfluoromethylpyridine DYES INTERMEDIATES

(2R)-1-{5-amino-2-[1-(benzyloxy)-2-methyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol

(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol

(2R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-o

1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-

(R)-1-(5-aMino-2-(1-(benzyloxy)-2-Methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol

1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-8

(2R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol

(2R)-1-{5-amino-2-[1-(benzyloxy)-2-methylpropan-2-yl]-6-fluoro-6,7-dihydro-1H-indol-1-yl}-3-(benzyloxy)propan-2-ol

Tezacaftor Intermediate

(2R)-1-[5-amino-6-fluoro-2-(2-methyl-1-phenylmethoxypropan-2-yl)indol-1-yl]-3-phenylmethoxypropan-2-ol

(2R)-1-{5-amino-2-[1-(benzyloxy)-2-methylpropan-2-yl]-6-fluo...

1H-Indole-1-ethanol, 5-aMino-2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-α-[(phenylMethoxy)Methyl]-, (αR)-

1294504-67-8

1295504-67-8

C29H33FN2O3