ChemicalBook > CAS DataBase List > 9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]-
9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]-
- Product Name
- 9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]-
- CAS No.
- 1353867-91-0
- Chemical Name
- 9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]-
- Synonyms
- Reaxys ID: 25796871;Longdaysin, 10 mM in DMSO;9-propan-2-yl-N-[[3-(trifluoromethyl)phenyl]methyl]purin-6-amine;9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]-;ERK,Cyclin dependent kinase,inhibit,CDK,Inhibitor,Longdaysin,Casein Kinase,Extracellular signal regulated kinases
- CBNumber
- CB32667961
- Molecular Formula
- C16H16F3N5
- Formula Weight
- 335.33
- MOL File
- 1353867-91-0.mol
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9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]- Property
- Boiling point:
- 447.6±55.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- DMSO : 125 mg/mL (372.77 mM);Water : < 0.1 mg/mL (insoluble)
- pka
- 3.42±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0007385
- Product name
- Longdaysin
- Purity
- 99.92%
- Packaging
- 5mg
- Price
- $110
- Updated
- 2021/12/16
Axon Medchem
- Product number
- Axon2998
- Product name
- Longdaysin
- Purity
- 99%
- Packaging
- 10mg
- Price
- $137.5
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0007385
- Product name
- Longdaysin
- Purity
- 99.92%
- Packaging
- 10mg
- Price
- $180
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0007385
- Product name
- Longdaysin
- Purity
- 99.92%
- Packaging
- 25mg
- Price
- $390
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0009855
- Product name
- LONGDAYSIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $456.05
- Updated
- 2021/12/16
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9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]- Chemical Properties,Usage,Production
Uses
Longdaysin may be used to study cell signaling th at regulate the circadian clock and behavior.
Biological Activity
Longdaysin inhibits CK1, ERK2, and CDK7 kinases in low mM concentrations. The activity of longdaysin results in a lengthening of circadian periods in cell based and in vivo systems. Transgenic zebrafish harboring a per3-luc reporter gene displayed a 10 hour lengthening of circadian period when treated with longdaysin. Longdaysin reduces the phosphorylation of PER1 the regulator of molecular clock function and manipulates the circadian clock.
9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
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9H-Purin-6-aMine, 9-(1-Methylethyl)-N-[[3-(trifluoroMethyl)phenyl]Methyl]- Suppliers
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