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Dantrolene-d4

Product Name
Dantrolene-d4
CAS No.
2749234-17-9
Chemical Name
Dantrolene-d4
Synonyms
Dantrolene-d4
CBNumber
CB32673946
Molecular Formula
C14H6D4N4O5
Formula Weight
318.28
MOL File
2749234-17-9.mol
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Dantrolene-d4 Property

solubility 
DMSO: soluble
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29451
Product name
Dantrolene-d4
Packaging
1mg
Price
$213
Updated
2024/03/01
Usbiological
Product number
445780
Product name
Dantrolene-D4
Packaging
1mg
Price
$460
Updated
2021/12/16
TRC
Product number
D185001
Product name
Dantrolene-D4
Packaging
10mg
Price
$1320
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
RDL0006742
Product name
DANTROLENE-D4
Purity
95.00%
Packaging
5MG
Price
$499.61
Updated
2021/12/16
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Dantrolene-d4 Chemical Properties,Usage,Production

Uses

Dantrolene-D4 is the deuterium labelled analogue of Dantrolene Sodium Salt Hemiheptahydrate (D185000), which is a (skeletal) muscle relaxant, used in the treatment of malignant hyperthermia.

References

[1] MD S K, PHD  Masafumi Y M, PHD , et al. Dantrolene, a Therapeutic Agent for Malignant Hyperthermia, Markedly Improves the Function of Failing Cardiomyocytes by Stabilizing Interdomain Interactions Within the Ryanodine Receptor[J]. Journal of the American College of Cardiology, 2009, 53 21: Pages 1993-2005. DOI: 10.1016/j.jacc.2009.01.065
[2] YE WIN OO. Essential Role of Calmodulin in RyR Inhibition by Dantrolene.[J]. Molecular Pharmacology, 2015, 88 1: 57-63. DOI: 10.1124/mol.115.097691
[3] B A KOTSIAS  S M. Reversible effect of dantrolene sodium on twitch tension of rat skeletal muscle.[J]. Archives of neurology, 1978, 35 4: 234-236. DOI: 10.1001/archneur.1978.00500280052010
[4] T E NELSON  E H F. Rationale for dantrolene vs. procainamide for treatment of malignant hyperthermia.[J]. Anesthesiology, 1979, 50 2: 118-122. DOI: 10.1097/00000542-197902000-00008

Dantrolene-d4 Preparation Products And Raw materials

Raw materials

Preparation Products

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Dantrolene-d4 Suppliers

SynZeal Research Pvt Ltd
Tel
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Fax
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Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
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