1H-BENZOTRIAZOLE-1-METHANOL
- Product Name
- 1H-BENZOTRIAZOLE-1-METHANOL
- CAS No.
- 28539-02-8
- Chemical Name
- 1H-BENZOTRIAZOLE-1-METHANOL
- Synonyms
- NSC 12463;AKOS 92621;AURORA 19841;Benzotriazolemethanol;1-Benzotriazolemethanol;BENZOTRIAZOL-1-YL-METHANOL;1H-BENZOTRIAZOLE-1-METHANOL;1H-Benzotriazol-1-ylmethanol;1-HydroxyMethyl benzotriazole;1H-Benzotriazole-1-Methanol 98%
- CBNumber
- CB3267637
- Molecular Formula
- C7H7N3O
- Formula Weight
- 149.15
- MOL File
- 28539-02-8.mol
1H-BENZOTRIAZOLE-1-METHANOL Property
- Melting point:
- 150-152 °C (lit.)
- Boiling point:
- 340.2±25.0 °C(Predicted)
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- pka
- 12.80±0.10(Predicted)
- color
- White to Almost white
- InChI
- InChI=1S/C7H7N3O/c11-5-10-7-4-2-1-3-6(7)8-9-10/h1-4,11H,5H2
- InChIKey
- MXJIHEXYGRXHGP-UHFFFAOYSA-N
- SMILES
- N1(CO)C2=CC=CC=C2N=N1
- CAS DataBase Reference
- 28539-02-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 410233
- Product name
- 1H-Benzotriazole-1-methanol
- Purity
- 98%
- Packaging
- 10g
- Price
- $53.3
- Updated
- 2025/07/31
- Product number
- 410233
- Product name
- 1H-Benzotriazole-1-methanol
- Purity
- 98%
- Packaging
- 50g
- Price
- $167.44
- Updated
- 2025/07/31
- Product number
- B1903
- Product name
- 1H-Benzotriazole-1-methanol
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $52
- Updated
- 2025/07/31
- Product number
- B207548
- Product name
- 1H-Benzotriazole-1-methanol
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B207548
- Product name
- 1H-Benzotriazole-1-methanol
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
1H-BENZOTRIAZOLE-1-METHANOL Chemical Properties,Usage,Production
Uses
Catalyst for:
- Hydrolysis of phenyl esters of a-furoic acid
Used as:
- Corrosion inhibitor of iron in aerated acidic media
- Reactive oxygen scavenger
Reactant for:
- Synthesis of hydroxy-skipped bis-homo-inositols as potential glycosidase inhibitors via Sharpless asymmetric dihydroxylation and substrate-directed anionic hydroxymethylation
- Enantioselective synthesis of aplysin utilizing a palladium-catalyzed addition of an arylboronic acid to an allenic alcohol, followed by Eschenmoser/Claisen rearrangement
- Synthesis of substituted dihydroquinoline carboxylic acids as antitumor and HIV-1 integrase inhibitors
- Gosteli-Claisen rearrangement
reaction suitability
reaction type: C-C Bond Formation
Synthesis
95-14-7
50-00-0
28539-02-8
Example 30 Synthesis of 1H-benzotriazole-1-methanol: 10 g (83.94 mmol) of 1H-benzotriazole was dissolved in 6.81 mL (83.94 mmol) of 37% formaldehyde aqueous solution. The temperature of the mixture was adjusted to 25°C under stirring. After 5 minutes of reaction, the mixture was cured. Subsequently, the reaction mixture was cooled to room temperature, filtered and washed with ether. The resulting solid was ground in cold tetrahydrofuran and filtered again (Int.94). Product yield: 94%, melting point: 148-150°C (determined by recrystallization from tetrahydrofuran and ether).
References
[1] Patent: US2004/67998, 2004, A1. Location in patent: Page/Page column 24
[2] Journal of the American Chemical Society, 2017, vol. 139, # 27, p. 9281 - 9290
[3] Patent: CN102688233, 2016, B. Location in patent: Paragraph 0095; 0098
[4] Patent: CN106188103, 2016, A. Location in patent: Paragraph 0035; 0037
[5] Journal of the American Chemical Society, 1952, vol. 74, p. 3868
1H-BENZOTRIAZOLE-1-METHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-BENZOTRIAZOLE-1-METHANOL manufacturers
- Product
- benzotriazol-1-ylmethanol 28539-02-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.4%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 1H-Benzotriazole-1-methanol 28539-02-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 1H-BENZOTRIAZOLE-1-METHANOL 28539-02-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-02