ChemicalBook > CAS DataBase List > HBX 19818
HBX 19818
- Product Name
- HBX 19818
- CAS No.
- 1426944-49-1
- Chemical Name
- HBX 19818
- Synonyms
- HBX 19818;HBX19818; HBX-19818;HBX 19818, 10 mM in DMSO;HBX 19818,Deubiquitinase,Inhibitor,DUBs,HBX19818,inhibit,HBX-19818;N-[3-[benzyl(methyl)amino]propyl]-9-chloro-5,6,7,8-tetrahydroacridine-2-carboxamide;9-Chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-2-acridinecarboxamide;2-Acridinecarboxamide, 9-chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-
- CBNumber
- CB32682003
- Molecular Formula
- C25H28ClN3O
- Formula Weight
- 421.96
- MOL File
- 1426944-49-1.mol
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HBX 19818 Property
- Boiling point:
- 631.2±55.0 °C(Predicted)
- Density
- 1.206±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:12.5(Max Conc. mg/mL);29.62(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.47(Max Conc. mM)
Water:5.0(Max Conc. mg/mL);0.47(Max Conc. mM) - form
- Solid
- pka
- 13.67±0.20(Predicted)
- color
- Light yellow to yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-2271
- Product name
- HBX19818
- Purity
- 98.93%
- Packaging
- 5mg
- Price
- $160
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-2271
- Product name
- HBX19818
- Purity
- 98.93%
- Packaging
- 10mg
- Price
- $250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-2271
- Product name
- HBX19818
- Purity
- 98.93%
- Packaging
- 50mg
- Price
- $850
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-2271
- Product name
- HBX19818
- Purity
- 98.93%
- Packaging
- 100mg
- Price
- $1100
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC10354
- Product name
- HBX19818
- Purity
- >98%
- Packaging
- 1g
- Price
- $3600
- Updated
- 2021/12/16
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HBX 19818 Chemical Properties,Usage,Production
Uses
HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM.
References
[1] Reverdy C, et al. Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. Chem Biol. 2012 Apr 20;19(4):467-77. DOI:10.1016/j.chembiol.2012.02.007
HBX 19818 Preparation Products And Raw materials
Raw materials
Preparation Products
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