1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzene

Product Name: 1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzene
CAS No.: 170098-98-3
Chemical Name: 1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzene
Synonyms: 2-BroMo-5-fluoro-4-nitrotoluene;2-Bromo-5-fluoro-4-nitrotoluene97%;2-Bromo-5-fluoro-4-nitrotoluene 97%;5-BroMo-2-fluoro-4-Methylnitrobenzene;4-Fluoro-2-methyl-5-nitrobromobenzene;1-Bromo-4-fluoro-2-methyl-5-nitrobenzene;Benzene, 1-bromo-4-fluoro-2-methyl-5-nitro-;1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzene
CBNumber: CB32699409
Molecular Formula: C7H5BrFNO2
Formula Weight: 234.02
MOL File: 170098-98-3.mol

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1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzene Property

Boiling point:: 290.7±35.0 °C(Predicted)
Density: 1.696±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly)
form: Solid
color: White to Off-White
InChI: InChI=1S/C7H5BrFNO2/c1-4-2-6(9)7(10(11)12)3-5(4)8/h2-3H,1H3
InChIKey: VMXDJIHJOUZBAW-UHFFFAOYSA-N
SMILES: C1(Br)=CC([N+]([O-])=O)=C(F)C=C1C

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Safety

HS Code: 2904990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B692588
Product name: 1-Bromo-4-fluoro-2-methyl-5-nitrobenzene
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Usbiological

Product number: 409350
Product name: 1-Bromo-4-fluoro-2-methyl-5-nitrobenzene
Packaging: 100mg
Price: $305
Updated: 2021/12/16

Apolloscientific

Product number: PC51134
Product name: 2-Bromo-5-fluoro-4-nitrotoluene
Purity: 97%
Packaging: 1g
Price: $73
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4754-B-X2
Product name: 2-Bromo-5-fluoro-4-nitrotoluene
Purity: 97%
Packaging: 1g
Price: $80
Updated: 2021/12/16

AK Scientific

Product number: X8161
Product name: 1-Bromo-4-fluoro-2-methyl-5-nitrobenzene
Packaging: 1g
Price: $84
Updated: 2021/12/16

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1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzene Chemical Properties,Usage,Production

Synthesis

452-63-1

170098-98-3

Step 1: Nitration reaction Suspend 2.21 g (16.7 mmol) of nitronium tetrafluoroborate in 30 mL of dichloromethane. Under reflux conditions, 3.0 g (15.9 mmol) of 2-bromo-5-fluorotoluene dissolved in 30 mL of dichloromethane was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was continued to be stirred under reflux conditions for 6 hours. Upon completion of the reaction, the mixture was poured into ice water and extracted with dichloromethane. The organic phases were combined, washed with water, dried over anhydrous sodium sulfate and subsequently concentrated on a rotary evaporator to give a yellow oil. The oil was allowed to stand overnight and the oil crystallized. The crystals were collected by filtration, washed with 2 mL of pentane and dried to give 265 mg (6.9% yield) of the target product 1-bromo-4-fluoro-2-methyl-5-nitrobenzene. The product was analyzed by GC/MS (Method 8, EIpos): retention time Rt = 4.49 min, mass-to-charge ratio m/z = 232/234 [M]+.

References

[1] Patent: WO2007/36718, 2007, A2. Location in patent: Page/Page column 57-58
[2] Patent: US2005/154020, 2005, A1. Location in patent: Page/Page column 8-9
[3] Patent: US2005/154022, 2005, A1. Location in patent: Page/Page column 9
[4] Patent: US2006/79523, 2006, A1. Location in patent: Page/Page column 13
[5] Patent: US2006/79524, 2006, A1. Location in patent: Page/Page column 13

1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzene Suppliers

China 54 India 1 United Kingdom 1 United States 4 Global 60

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170098-98-3, 1-Bromo-4-fluoro-2-methyl-5-nitrobenzene, 5-Bromo-2-fluoro-4-methylnitrobenzeneRelated Search:

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