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UNC0379 (trifluoroacetate)

Product Name
UNC0379 (trifluoroacetate)
CAS No.
1620401-83-3
Chemical Name
UNC0379 (trifluoroacetate)
Synonyms
UNC0379 TFA;UNC0379 (trifluoroacetate);UNC0379 trifluoroacetate salt;UNC0379 trifluoroacetate salt >=98% (HPLC)
CBNumber
CB32735543
Molecular Formula
C25H36F3N5O4
Formula Weight
527.59
MOL File
1620401-83-3.mol
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UNC0379 (trifluoroacetate) Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
color 
Light yellow to khaki
Water Solubility 
H2O: 5mg/mL, clear
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-3606
Product name
UNC0379TFA
Purity
99.91%
Packaging
2mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-3606
Product name
UNC0379TFA
Purity
99.91%
Packaging
5mg
Price
$120
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611655
Product name
UNC0379 trifluoroacetate
Packaging
100mg
Price
$765
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611655
Product name
UNC0379 trifluoroacetate
Packaging
250mg
Price
$1504.5
Updated
2021/12/16
DC Chemicals
Product number
DC23217
Product name
UNC0379trifluoroacetate
Purity
>98%
Packaging
1g
Price
$2000
Updated
2021/12/16
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UNC0379 (trifluoroacetate) Chemical Properties,Usage,Production

Biological Activity

SETD8 expression is observed in cancers such as bladder cancer, chronic myelogenous leukemia, hepatocellular carcinoma, non‐small‐cell lung carcinoma, prostate cancer, small‐cell lung carcinoma. Therefore inhibition of SETD8 (SET‐domain containing protein) by UNC0379 might prevent the progression of cancer.', 'UNC0379 is the first substrate-competitive inhibitor of the lysine methyltransferase SETD8, the only known methyltransferase th at catalyzes monomethylation of histone H4 lysine 20 (H4K20). HK420 methylation has been implicated in the regulation of a variety of biological processes including the DNA damage response. UNC0379 is selective for SETD8 over 15 other methyltransferases, with an IC50 value of 7.3 μM for SETD8 compared to IC50 vlaues over 100 μM for other methyltransferases.

UNC0379 (trifluoroacetate) Preparation Products And Raw materials

Raw materials

Preparation Products

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UNC0379 (trifluoroacetate) Suppliers

Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai Zeye Biotechnology Co., Ltd.
Tel
021-61998551 13122364865
Email
sale1@shzysw.net
Country
China
ProdList
9772
Advantage
58

1620401-83-3, UNC0379 (trifluoroacetate)Related Search:


  • UNC0379 (trifluoroacetate)
  • UNC0379 TFA
  • UNC0379 trifluoroacetate salt >=98% (HPLC)
  • UNC0379 trifluoroacetate salt
  • 1620401-83-3
  • C25H36F3N5O4