ChemicalBook > CAS DataBase List > T-00127-HEV1

T-00127-HEV1

Product Name
T-00127-HEV1
CAS No.
900874-91-1
Chemical Name
T-00127-HEV1
Synonyms
T-00127-HEV1;T00127-HEV1;T 00127 HEV1;T-00127_HEV1, 10 mM in DMSO;3-(3,4-Dimethoxyphenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine;Pyrazolo[1,5-a]pyrimidin-7-amine, 3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-[2-(4-morpholinyl)ethyl]-;PI4 kinases,Inhibitor,PI4K,Phosphatidylinositol 4 kinases,T00127_HEV1,T-00127_HEV1,inhibit,T-00127_HEV-1,T 00127_HEV1
CBNumber
CB32744615
Molecular Formula
C22H29N5O3
Formula Weight
411.5
MOL File
900874-91-1.mol
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T-00127-HEV1 Property

Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
6.72±0.10(Predicted)
form 
Solid
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
5.38001
Product name
T-00127-HEV1 - CAS 900874-91-1 - Calbiochem
Purity
A potent & selective PI4KIIIb inhibitor that displays antienteroviral activity. Dose-dependently inhibits viral RNA replication and inactive towards HCV.
Packaging
10MG
Price
$172
Updated
2022/05/15
ChemScene
Product number
CS-7907
Product name
T-00127_HEV1
Purity
99.97%
Packaging
5mg
Price
$350
Updated
2021/12/16
AK Scientific
Product number
SYN5471
Product name
T-00127-HEV1
Packaging
100mg
Price
$2171
Updated
2021/12/16
DC Chemicals
Product number
DC8063
Product name
T-00127-HEV1
Purity
>98%
Packaging
100mg
Price
$500
Updated
2021/12/16
DC Chemicals
Product number
DC8063
Product name
T-00127-HEV1
Purity
>98%
Packaging
250mg
Price
$900
Updated
2021/12/16
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T-00127-HEV1 Chemical Properties,Usage,Production

Uses

T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC50 of 60 nM.

Biological Activity

Cell permeable: yes', 'Primary Target
PI4KIIIβ', 'Reversible: yes', 'Target IC50: 150 nM for PI4KIII&beta

IC 50

PI4KB: 60 nM (IC50)

References

[1] Arita M, et al. Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity. J Virol. 2011 Mar;85(5):2364-72. DOI:10.1128/JVI.02249-10

T-00127-HEV1 Preparation Products And Raw materials

Raw materials

Preparation Products

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T-00127-HEV1 Suppliers

China 29 Finland 1 United States 3 Global 33
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
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58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
1014988033@qq.com
Country
China
ProdList
4941
Advantage
55
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 18438616290
Email
lanwu@univ-bio.com
Country
China
ProdList
24731
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
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58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
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58
Hefei Mokai Pharmaceutical Technology Co., Ltd
Tel
18130062233
Email
3362556465@qq.com
Country
China
ProdList
8100
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58

900874-91-1, T-00127-HEV1Related Search:


  • T-00127-HEV1
  • T00127-HEV1;T 00127 HEV1
  • Pyrazolo[1,5-a]pyrimidin-7-amine, 3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-[2-(4-morpholinyl)ethyl]-
  • PI4 kinases,Inhibitor,PI4K,Phosphatidylinositol 4 kinases,T00127_HEV1,T-00127_HEV1,inhibit,T-00127_HEV-1,T 00127_HEV1
  • 3-(3,4-Dimethoxyphenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine
  • T-00127_HEV1, 10 mM in DMSO
  • 900874-91-1