ChemicalBook > CAS DataBase List > 7-Fluoro-4-hydroxy-2H-chromen-2-one

7-Fluoro-4-hydroxy-2H-chromen-2-one

Product Name
7-Fluoro-4-hydroxy-2H-chromen-2-one
CAS No.
2145-27-9
Chemical Name
7-Fluoro-4-hydroxy-2H-chromen-2-one
Synonyms
7-Fluoro-4-hydroxycoumarin;7-Fluoro-4-hydroxy-2H-chromen-2-one;7-Fluoro-4-hydroxy-2H-1-benzopyran-2-one;7-Fluoro-4-hydroxy-1(2H)-benzopyran-2-one;2H-1-Benzopyran-2-one, 7-fluoro-4-hydroxy-
CBNumber
CB32755514
Molecular Formula
C9H5FO3
Formula Weight
180.13
MOL File
2145-27-9.mol
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7-Fluoro-4-hydroxy-2H-chromen-2-one Property

Melting point:
220-225°C
Boiling point:
339.4±42.0 °C(Predicted)
Density 
1.549±0.06 g/cm3(Predicted)
storage temp. 
Store at room temperature
pka
4.50±1.00(Predicted)
form 
solid
Appearance
White to off-white Solid
InChI
1S/C9H5FO3/c10-5-1-2-6-7(11)4-9(12)13-8(6)3-5/h1-4,11H
InChIKey
FSWKHPJLMMGTBV-UHFFFAOYSA-N
SMILES
OC1=CC(=O)Oc2cc(F)ccc12
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
732982
Product name
7-Fluoro-4-hydroxycoumarin
Packaging
250mg
Price
$152
Updated
2023/06/20
TRC
Product number
F600573
Product name
7-fluoro-4-hydroxy-2H-chromen-2-one
Packaging
50mg
Price
$175
Updated
2021/12/16
TRC
Product number
F600573
Product name
7-fluoro-4-hydroxy-2H-chromen-2-one
Packaging
100mg
Price
$285
Updated
2021/12/16
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7-Fluoro-4-hydroxy-2H-chromen-2-one Chemical Properties,Usage,Production

Uses

Reactant for:

  • Enantioselective synthesis of polycyclic coumarins via in situ formed primary amine-imine-catalyzed asymmetric Michael addition to cyclic enones
  • Preparation of dicoumarol analogs as inhibitors of human NAD(P)H quinone oxidoreductase-1 (NQO1) as agents active against human pancreatic and colon cancer cells
  • Imidazolidinecarboxylic acid-catalyzed asymmetric Michael reaction with unsaturated ketones in a highly atom-economic catalytic one-step formation of optically active warfarin anticoagulant
  • Asymmetric synthesis of functionalized α-keto esters and their hemiketal and hemiaminal derivatives via direct Michael addition with unsaturated α-keto esters catalyzed by bisoxazoline-copper(II) complexes

7-Fluoro-4-hydroxy-2H-chromen-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Fluoro-4-hydroxy-2H-chromen-2-one Suppliers

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
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80
Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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86249
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60
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
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China
ProdList
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Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ:2853979817
Email
3983243027@qq.com
Country
China
ProdList
9800
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3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
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Chongqing Zhisheng Technology Co., Ltd.
Tel
023-67586781 17783613370
Fax
QQ 2636861874
Email
2636861874@qq.com
Country
China
ProdList
446
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Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
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Chemwill Asia Co.,Ltd.
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86-21-51086038
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86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
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Shanghai TenSus Biotechnology Co., Ltd.
Tel
021-50895067 18616507272
Fax
021-50895067
Email
tensus@163.com
Country
China
ProdList
8031
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58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
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China
ProdList
29795
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View Lastest Price from 7-Fluoro-4-hydroxy-2H-chromen-2-one manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
7-Fluoro-4-hydroxy-2H-chromen-2-one 2145-27-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-27
Career Henan Chemical Co
Product
7-Fluoro-4-hydroxy-2H-chromen-2-one 2145-27-9
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

2145-27-9, 7-Fluoro-4-hydroxy-2H-chromen-2-oneRelated Search:


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  • 7-Fluoro-4-hydroxy-2H-1-benzopyran-2-one
  • 2145-27-9
  • C9H5O3F