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Epidermal Growth Factor

Product Name
Epidermal Growth Factor
CAS No.
62253-63-8
Chemical Name
Epidermal Growth Factor
Synonyms
EGF;sh-Oligopeptide-1;HEGF;RHEGF;NepiderMin;rh-Oligopeptide-1;HUMAN EPIDERMAL GROWTH FACTOR;EGP;NMEGF;HOMG4
CBNumber
CB3295102
Molecular Formula
C270H401N73O83S7
Formula Weight
6221.96724
MOL File
62253-63-8.mol
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Epidermal Growth Factor Property

storage temp. 
-20°C
form 
powder
color 
white
InChIKey
GVUGOAYIVIDWIO-UFWWTJHBSA-N
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Safety

WGK Germany 
3
RTECS 
KB4518000
10-21
HS Code 
2937190000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E9644
Product name
hEGF
Purity
EGF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Packaging
0.2mg
Price
$254
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB4501796
Product name
Anti-TACD1 antibody produced in rabbit
Purity
affinity isolated antibody
Packaging
100μg
Price
$506
Updated
2024/03/01
Sigma-Aldrich
Product number
E9644
Product name
hEGF
Purity
EGF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Packaging
0.5mg
Price
$377
Updated
2024/03/01
Sigma-Aldrich
Product number
E5036
Product name
Epidermal Growth Factor, human, animal component free
Purity
EGF, recombinant, expressed in Escherichia coli, >97% (SDS-PAGE)
Packaging
200μg
Price
$358
Updated
2024/03/01
Sigma-Aldrich
Product number
E5036
Product name
Epidermal Growth Factor, human, animal component free
Purity
EGF, recombinant, expressed in Escherichia coli, >97% (SDS-PAGE)
Packaging
500μg
Price
$432
Updated
2024/03/01
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Epidermal Growth Factor Chemical Properties,Usage,Production

Description

An ophthalmic formulation of epidermal growth factor (urogastrone) has been launched for stimulation of healing of the corneal epithelium following various corneal diseases.

Chemical Properties

Endotoxin < 0.1 ng per μg (1EU/ug) of EGF

Originator

Inpharzam (Italy)

Uses

Epidermal Growth Factor, human, animal component free has been used:

  • as a supplement in in LHC-8 medium to culture liver cell lines
  • in the fetal bovine serum (FBS)-Dulbecco′s modified essential medium (DMEM) /F12 medium for primary culture of human glioma cells
  • as an additive in the conditional medium of normal fibroblasts (NFs) to study its effect on the migration and invasion of endometrial cancer (EC) cells
  • as a component in tumorsphere medium

Uses

EGF (epidermal growth factor) human has been used in the culture medium for the maintenance of MCF10A cells (human mammary epithelial cells).

Uses

This product is used as a mitogen, triggering the cell to commence mitosis, in a variety of cell lines. In tissue cultures, EGF acts to reduce or eliminate the requirement for serum and can be used in conjunction with other media additives and hormones.

Application

Epidermal Growth Factor (EGF) is a human protein that is involved in the regulation of cell growth, differentiation and survival. Recombinant EGF is an antigen binding molecule that can be used as a cancer treatment. Recombinant EGF has been shown to stimulate cellular transformation by binding to the epidermal growth factor receptor. It also has been shown to inhibit the growth of breast cancer cells with the HER2 gene mutation. The molecular weight of rec EGF is approximately 25 kDa and is composed of 165 amino acids. Recombinant EGF can be used in immunoassays, as a model system for studying biological properties, or as an antibody production tool.

brand name

Gentel

General Description

Epidermal Growth Factor (EGF) is a small mitogenic polypeptide (~6 kDa), which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids.? Human EGF is identical to β-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion.? EGF is a member of a growth factor family, which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF.? EGF is homologous to a sequence contained in a 19 kDa protein of vaccinia virus,? which appears to utilize the EGF receptor to gain entry into cell? EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.?

Biochem/physiol Actions

Epidermal growth factor (EGF) helps to induce cell growth, proliferation and differentiation. It participates in the repairing of renal tissues in the kidney. It promotes the reabsorption of magnesium with the help of the transient receptor potential cation channel 6 (TRMP6). EGF is known to participate in the pathophysiology of drug-induced renal magnesium loss.

Epidermal Growth Factor Preparation Products And Raw materials

Raw materials

Preparation Products

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Epidermal Growth Factor Suppliers

Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4852
Advantage
58
Shifang ShengYuan Technology Co., Ltd.
Tel
0838-6510595 13402890778 18881099744
Email
1120021438@qq.com
Country
China
ProdList
131
Advantage
56
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
6756
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48461
Advantage
58
ACROBiosystems
Tel
18514007688
Email
jiaxin.zhao@acrobiosystems.com
Country
China
ProdList
1066
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2964
Advantage
65
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from Epidermal Growth Factor manufacturers

Sinoway Industrial co., ltd.
Product
Epidermal Growth Factor / rhEGF 62253-63-8
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
1.0x10 7 IU/mg up
Supply Ability
20 tons
Release date
2022-08-22
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Epidermal Growth Factor 62253-63-8
Price
US $999.00-666.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-21
.GZ HONESTCHEM CO.,LTD
Product
EGF
Price
US $1.00/g/ml
Min. Order
1kit
Purity
99.9%
Supply Ability
100KG
Release date
2019-10-20

62253-63-8, Epidermal Growth FactorRelated Search:


  • RECOMBINANT MOUSE EGF
  • RECOMBINANT HUMAN EGF
  • REC EPIDERMAL GROWTH FACTOR (HUMAN)
  • REC EGF (HUMAN)
  • RHEGF
  • MURINE URG
  • MURINE UROGASTRONE
  • MOUSE EGF
  • MURINE EPIDERMAL GROWTH FACTOR
  • MURINE EGF
  • NMEGF
  • LONG EGF
  • MEGF (GRADE I)
  • EGF, HUMAN
  • EGF, MOUSE
  • EGF, MURINE
  • EGF, MURINE SUBMAXILLARY GLAND
  • EGF
  • EGP
  • EPIDERMAL GROWTH FACTOR, MURINE SUBMAXILLARY GLAND
  • EPIDERMAL GROWTH FACTOR, MURINE SUBMAXILLARY GLANDS
  • latrophilin and seven transmembrane domain-containing protein 1
  • Recombinant human epidermal growth factor (rhEGF) injectable grade
  • Recombinant human epidermalgrowth factor (rhEGF)
  • REC EPIDERMAL GROWTH FACTOR
  • rhEGF, Human Oligopeptide-1
  • sH-Oligopeptide-1, Nepidermin
  • EGF Antigen
  • URG, HOMG4
  • sh-Oligopeptide-1/rh-Oligopeptide-1 (Human EGF)
  • EGF,sh-oligopeptide-1,rh-EGF
  • EPIDERMAL GROWTH FACTOR, HUMAN
  • EPIDERMAL GROWTH FACTOR, HUMAN, RECOMBINANT
  • EPIDERMAL GROWTH FACTOR, MOUSE
  • EPIDERMAL GROWTH FACTOR, MOUSE (GRADE I)
  • EPIDERMAL GROWTH FACTOR, MURINE
  • EPIDERMAL GROWTH FACTOR (EGF) HUMAN
  • EPIDERMAL GROWTH FACTOR
  • HEGF
  • Human Oligopeptide-1
  • HUMAN UROGASTRONE
  • HUMAN URG
  • HUMAN EPIDERMAL GROWTH FACTOR
  • HUMAN EGF
  • ASN-SER-ASP-SER-GLU-CYS-PRO-LEU-SER-HIS-ASP-GLY-TYR-CYS-LEU-HIS-ASP-GLY-VAL-CYS-MET-TYR-ILE-GLU-ALA-LEU-ASP-LYS-TYR-ALA-CYS-ASN-CYS-VAL-VAL-GLY-TYR-ILE-GLY-GLU-ARG-CYS-GLN-TYR-ARG-ASP-LEU-LYS-TRP-TRP-GLU-LEU-ARG
  • *recombinant expres
  • EPIDERMAL GROWTH FACTOR HUMAN, RECOMBINA NT EXPRESSED IN E. COLI
  • a-EpiderMal growth factor (huMan)
  • Epidermal Growth Factor, human, animal component free
  • HOMG4
  • Anti-TACD1 antibody produced in rabbit
  • Epithelial cell surface antigen
  • Epithelial glycoprotein
  • Major gastrointestinal tumor-associated protein GA733-2
  • Tumor-associated calcium signal transducer 1
  • EGF-TM7-latrophilin-related protein
  • longtm egf human
  • Epidermal Growth Factor human,EGF