ChemicalBook > CAS DataBase List > N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE

N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE

Product Name
N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE
CAS No.
143457-40-3
Chemical Name
N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE
Synonyms
TAPI-O;TAPI-0;TNF-ALPHA PROTEASE INHIBITOR-O;TNF-ALPHA PROTEASE INHIBITOR-0;TAPI-0 (TNF-± processing inhibitor-0);HONHCOCH2CH(CH2-CH(CH3)2)CO-NAL-ALA-NH2;TAPI-0 (TNF alpha processing inhibitor-0);N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE;N-(R)-(2-(HYDROXYAMINOCARBONYL)METHYL)-4-METHYLPENTANOYL-L-3-(2'-NAPHTHYL) ALANYL-L-ALANINE AMIDE;N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1- oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide
CBNumber
CB3299443
Molecular Formula
C24H32N4O5
Formula Weight
456.53
MOL File
Mol file
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N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE Property

Density 
1.227±0.06 g/cm3(Predicted)
pka
9.17±0.20(Predicted)
form 
White powder.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
579050
Product name
TAPI-0 - CAS 143457-40-3 - Calbiochem
Packaging
1mg
Price
$490
Updated
2024/03/01
Tocris
Product number
5523
Product name
TAPI0
Purity
≥95%(HPLC)
Packaging
1
Price
$288
Updated
2021/12/16
TRC
Product number
T007300
Product name
TAPI-0
Packaging
500μg
Price
$120
Updated
2021/12/16
TRC
Product number
T007300
Product name
TAPI-0
Packaging
1mg
Price
$230
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000227
Product name
TAPI-0
Purity
95.00%
Packaging
1MG
Price
$455.7
Updated
2021/12/16
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N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE Chemical Properties,Usage,Production

Uses

TAPI-0 is an inhibitor which blocks the maturation of cytokines, soluble cyokine receptors and other proteins that require the action of proteases.

N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE Suppliers

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143457-40-3, N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDERelated Search:


  • HONHCOCH2CH(CH2-CH(CH3)2)CO-NAL-ALA-NH2
  • TAPI-0
  • TAPI-O
  • N-(R)-(2-(HYDROXYAMINOCARBONYL)METHYL)-4-METHYLPENTANOYL-L-3-(2'-NAPHTHYL) ALANYL-L-ALANINE AMIDE
  • N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE AMIDE
  • TNF-ALPHA PROTEASE INHIBITOR-0
  • TNF-ALPHA PROTEASE INHIBITOR-O
  • TAPI-0 (TNF-± processing inhibitor-0)
  • L-Alaninamide, N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl- (9CI)
  • N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1- oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide
  • TAPI-0 (TNF alpha processing inhibitor-0)
  • 143457-40-3
  • A hydroxamate-based inhibitor of collagenase, gelatinase, and TACE