N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite

Product Name: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
CAS No.: 171486-59-2
Chemical Name: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
Synonyms: 2'-O-Propargyl-A(Bz)-CE-Phosphoramidite;2'-O-Propargyl A(Bz)-3'-phosphoramidite;2’-O-Propargyl A(Bz)-3’-phosphoramidite;DMTr-2'-O-propargyl-rA(Bz)-3'-CE-Phosphoramidite;DMTr-2'-O-propargyl-rA(Bz)-3' -CE-Phosphoramidite;N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine3'-CEphosphoramidite;N6-Bz-5’-O-DMTr-2’-O-propargyladenosine-3’-CED-phosphora midite;N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite;N6-Bz-5’-O-DMTr-2’-O-propargyladenosine-3’-CED-phosphora midite, 2’-O-Propargyl A(Bz)-3’-phosphoramidite;N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
CBNumber: CB33035277
Molecular Formula: C50H54N7O8P
Formula Weight: 912
MOL File: 171486-59-2.mol

More

Less

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Property

pka: 7.87±0.43(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Chemical Properties,Usage,Production

Uses

2'-O-Propargyl A(Bz)-3'-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Suppliers

China 33 United States 3 Global 36

Zhengzhou GranLen pharmaceutical Technology Co., Ltd.

Tel: 0371-85513397
Email: info@granlen.com
Country: China
ProdList: 497
Advantage: 55

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Shanghai Xianggeng Technology Development Co. Ltd.

Tel: 021-021-56152668 18116302010
Fax: 18116300787
Email: sharing@sharingtechcn.com
Country: China
ProdList: 506
Advantage: 58

Zhengzhou Granlen Sciences, ltd.

Tel: 0371-85513397 +86-18610099868
Email: info@granlen.com
Country: China
ProdList: 1890
Advantage: 58

NewCan Biotech Limited

Tel: +86-0571-86912261 +8613735419629
Email: sales@newcanbio.com
Country: China
ProdList: 9985
Advantage: 58

Amel Pharmatech Corporation

Tel: 027-888-4366503
Fax: 888-502-1736
Email: sales@amelpharmatech.com
Country: China
ProdList: 5000
Advantage: 58

BOC Sciences

Tel: 16314854226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 9713
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Hefei Stongbio Co.,Ltd.

Tel: 15555170917
Email: sales@stongbio.com
Country: China
ProdList: 509
Advantage: 58

Wuhan Tangzhi Pharmaceutical Co., Ltd.

Tel: 027-63498076 13658392159
Email: sale@glycogene.com
Country: China
ProdList: 832
Advantage: 58

171486-59-2, N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramiditeRelated Search:

2'-O-Propargyl A(Bz)-3'-phosphoramidite

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladeno sine-3'-O-[(2-cyano-ethyl)-(N,N-diisopropyl)]phosphorami dite

N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

N6-Bz-5’-O-DMTr-2’-O-propargyladenosine-3’-CED-phosphora midite, 2’-O-Propargyl A(Bz)-3’-phosphoramidite

N6-Bz-5’-O-DMTr-2’-O-propargyladenosine-3’-CED-phosphora midite

DMTr-2'-O-propargyl-rA(Bz)-3'-CE-Phosphoramidite

2’-O-Propargyl A(Bz)-3’-phosphoramidite

N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine3'-CEphosphoramidite

2'-O-Propargyl-A(Bz)-CE-Phosphoramidite

DMTr-2'-O-propargyl-rA(Bz)-3' -CE-Phosphoramidite

Adenosine, N-?benzoyl-?5'-?O-?[bis(4-?methoxyphenyl)?phenylmethyl]?-?2'-?O-?2-?propyn-?1-?yl-?, 3'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite

171486-59-2

C50H54N7O8P

2'-O-Propargyl