Syk Inhibitor II

Product Name: Syk Inhibitor II
CAS No.: 227449-73-2
Chemical Name: Syk Inhibitor II
Synonyms: Syk Inhibitor II;Syk Inhibitor II (hydrochloride);Syk Inhibitor II dihydrochloride;Syk Inhibitor II dihydrochloride, 10 mM in DMSO;2-[(2-Aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamide Hydrochloride
CBNumber: CB33036911
Molecular Formula: C14H16ClF3N6O
Formula Weight: 376.77
MOL File: 227449-73-2.mol

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Syk Inhibitor II Property

storage temp.: Store at -20°C
solubility: DMF: 2 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.3 mg/ml; PBS (pH 7.2): 10 mg/ml
form: A crystalline solid
color: off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 574712
Product name: Syk Inhibitor II - CAS 227449-73-2 - Calbiochem
Packaging: 1mg
Price: $404
Updated: 2023/01/07

Cayman Chemical

Product number: 18805
Product name: Syk Inhibitor II (hydrochloride)
Purity: ≥98%
Packaging: 500μg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 18805
Product name: Syk Inhibitor II (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $228
Updated: 2024/03/01

Cayman Chemical

Product number: 18805
Product name: Syk Inhibitor II (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $952
Updated: 2024/03/01

TRC

Product number: S900000
Product name: 2-[(2-Aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamideHydrochloride
Packaging: 0.5mg
Price: $125
Updated: 2021/12/16

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Syk Inhibitor II Chemical Properties,Usage,Production

Uses

2-[(2-Aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamide Hydrochloride was identified via a small molecule screening assay. In addition, this compound inhibits tyrosine kinase and may be a useful reagent to investigate cellular signalling pathways.

Biological Activity

Cell permeable: yes', 'Primary Target
Syk', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 41 nM against Syk; 460 nM against FcεRI-mediated 5-HT release in RBL-2H3 cells in vitro

Syk Inhibitor II Preparation Products And Raw materials

Raw materials

Preparation Products

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Syk Inhibitor II Suppliers

China 25 United States 4 Global 29

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TargetMol Chemicals Inc.

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227449-73-2, Syk Inhibitor IIRelated Search:

Syk Inhibitor II

Syk Inhibitor II (hydrochloride)

2-[(2-Aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamide Hydrochloride

Syk Inhibitor II dihydrochloride

Syk Inhibitor II dihydrochloride, 10 mM in DMSO

227449-73-2