Ethylene Glycol 1,2-Bis(2-propynyl) Ether
- Product Name
- Ethylene Glycol 1,2-Bis(2-propynyl) Ether
- CAS No.
- 40842-04-4
- Chemical Name
- Ethylene Glycol 1,2-Bis(2-propynyl) Ether
- Synonyms
- Bis-propargyl-PEG1;Alkyne-PEG2-Alkyne;4,7-Dioxa-1,9-decadiyne;4,7-Dioxo-1,9-Decadiyne;PROPARGYL-PEG2-PROPARGYL;Propargyl-PEG1-Propargyl;1,2-Bis(propargyloxy)ethane;1,2-Bis(2-propynyloxy)ethane;1,2-bis(prop-2-yn-1-yloxy)ethane;ethylene glycol dipropargyl ether
- CBNumber
- CB33038304
- Molecular Formula
- C8H10O2
- Formula Weight
- 138.16
- MOL File
- 40842-04-4.mol
Ethylene Glycol 1,2-Bis(2-propynyl) Ether Property
- Boiling point:
- 88°C/15mmHg(lit.)
- Density
- 0.9502 g/cm3
- refractive index
- 1.4550 to 1.4590
- Flash point:
- 58°
- storage temp.
- 2-8°C, stored under nitrogen
- solubility
- Soluble in DMSO, DCM, DMF
- form
- clear liquid
- color
- White to Yellow to Green
Safety
- RIDADR
- UN 3271 3/PG III
- HS Code
- 2909.19.6000
- HazardClass
- 3
- PackingGroup
- III
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
N-Bromosuccinimide Price
- Product number
- E1054
- Product name
- Ethylene Glycol 1,2-Bis(2-propynyl) Ether
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $213
- Updated
- 2025/07/31
- Product number
- E1054
- Product name
- Ethylene Glycol 1,2-Bis(2-propynyl) Ether
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $737
- Updated
- 2025/07/31
- Product number
- B523148
- Product name
- bis-Propargyl-PEG2
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- AS107622
- Product name
- 1,2-Bis(propargyloxy)ethane
- Purity
- 97%
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 39705
- Product name
- Ethyleneglycol1,2-bis(2-propynyl)ether,97%(GC)
- Purity
- 97%(GC)
- Packaging
- 5G
- Price
- $211.68
- Updated
- 2021/12/16
Ethylene Glycol 1,2-Bis(2-propynyl) Ether Chemical Properties,Usage,Production
Description
Bis-propargyl-PEG2 is a homobifunctional PEG linker with two propargyl groups. The propargyl groups forms triazole linkage with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry.
Uses
Bis-propargyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-propargyl-PEG1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Ethylene Glycol 1,2-Bis(2-propynyl) Ether Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethylene Glycol 1,2-Bis(2-propynyl) Ether manufacturers
- Product
- Bis-propargyl-PEG2 40842-04-4
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-26
- Product
- ethylene glycol dipropargyl ether 40842-04-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.2%
- Supply Ability
- 100 tons
- Release date
- 2022-01-17