ciraparantag,Aripazine,PER977

Product Name: ciraparantag,Aripazine,PER977
CAS No.: 1438492-26-2
Chemical Name: ciraparantag,Aripazine,PER977
Synonyms: PER977;PER-977;PER 977;Aripazine;Ciraparantag;PER977; ARIPAZINE;Ciraparantag(PER977);di-arginine piperazine;ciraparantag,Aripazine,PER977;PER977; ARIPAZINE;PER-977;PER 977
CBNumber: CB33038531
Molecular Formula: C22H48N12O2
Formula Weight: 512.7
MOL File: 1438492-26-2.mol

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ciraparantag,Aripazine,PER977 Property

Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 15.11±0.46(Predicted)
form: Solid
color: White to off-white
Water Solubility: Water : ≥ 31 mg/mL (60.46 mM)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD31003480
Product name: Ciraparantag
Purity: 98+%
Packaging: 5mg
Price: $196
Updated: 2021/12/16

Crysdot

Product number: CD31003480
Product name: Ciraparantag
Purity: 98+%
Packaging: 10mg
Price: $315
Updated: 2021/12/16

Crysdot

Product number: CD31003480
Product name: Ciraparantag
Purity: 98+%
Packaging: 50mg
Price: $665
Updated: 2021/12/16

Chemenu

Product number: CM169989
Product name: (2S,2''S)-N,N''-(piperazine-1,4-diylbis(propane-3,1-diyl))bis(2-amino-5-guanidinopentanamide)
Purity: 98%
Packaging: 100mg
Price: $982
Updated: 2021/12/16

Crysdot

Product number: CD31003480
Product name: Ciraparantag
Purity: 98+%
Packaging: 100mg
Price: $1050
Updated: 2021/12/16

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ciraparantag,Aripazine,PER977 Chemical Properties,Usage,Production

Uses

Ciraparantag is a thrombin and factor Xa inhibitor. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including low-molecular-weight heparin, unfractionated heparin, and certain direct oral anticoagulants. It is reported to antagonize the effects of all coagulants except VKAs and agratroban[1][2][3][4].

References

[1] Das A, et al. Novel antidotes for target specific oral anticoagulants. Exp Hematol Oncol. 2015 Sep 15;4:25. DOI:10.1186/s40164-015-0020-3
[2] Gomez-Outes A, et al. Specific antidotes in development for reversal of novel anticoagulants: a review. Recent Pat Cardiovasc Drug Discov. 2014;9(1):2-10. DOI:10.2174/1574890109666141205132531
[3] Hu TY, et al. Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab. Vasc Health Risk Manag. 2016 Feb 17;12:35-44. DOI:10.2147/VHRM.S89130
[4] Honickel M, et al. The Reversal of Direct Oral Anticoagulants in Animal Models. Shock. 2017 Aug;48(2):144-158. DOI:10.1097/SHK.0000000000000848

ciraparantag,Aripazine,PER977 Preparation Products And Raw materials

Raw materials

Preparation Products

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ciraparantag,Aripazine,PER977 Suppliers

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1438492-26-2, ciraparantag,Aripazine,PER977Related Search:

ciraparantag,Aripazine,PER977

Ciraparantag

(2S,2'S)-N,N'-(1,4-Piperazinediyldi-3,1-propanediyl)bis[2-amino-5-[(aminoiminomethyl)amino]pentanamide]

PER977; ARIPAZINE

Aripazine

PER 977

PER977

PER-977

PER977; ARIPAZINE;PER-977;PER 977

Ciraparantag(PER977)

di-arginine piperazine

Pentanamide, N,N'-(1,4-piperazinediyldi-3,1-propanediyl)bis[2-amino-5-[(aminoiminomethyl)amino]-, (2S,2'S)-

(2S,2'S)-N,N'-(piperazine-1,4-diylbis(propane-3,1-diyl))bis(2-amino-5-guanidinopentanamide)

1438492-26-2

C22H48N12O2