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Ca2+ channel agonist 1

Product Name
Ca2+ channel agonist 1
CAS No.
1402821-24-2
Chemical Name
Ca2+ channel agonist 1
Synonyms
Ca2+ channel a onist 1;Ca2+ channel agonist 1;Ca2+ channel agonist 1, 10 mM in DMSO;(R)-2-((6-(Benzylamino)-9-propyl-9H-purin-2-yl)amino)butan-1-ol;1-Butanol, 2-[[6-[(phenylmethyl)amino]-9-propyl-9H-purin-2-yl]amino]-, (2R)-;Ca2+ channels,Calcium Channel,Ca2+ channel agonist 1,Inhibitor,inhibit,Ca channels,Cyclin dependent kinase,CDK,Ca-2+ channel agonist 1
CBNumber
CB33053880
Molecular Formula
C19H26N6O
Formula Weight
354.45
MOL File
1402821-24-2.mol
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Ca2+ channel agonist 1 Property

storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (141.06 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-5169
Product name
Ca2+channelagonist1
Purity
99.65%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-5169
Product name
Ca2+channelagonist1
Purity
99.65%
Packaging
10mg
Price
$600
Updated
2021/12/16
Crysdot
Product number
CD31003614
Product name
Ca2+channelagonist1
Purity
98+%
Packaging
50mg
Price
$1042
Updated
2021/12/16
DC Chemicals
Product number
DC8704
Product name
Ca2+channelagonist1
Purity
>98%
Packaging
250mg
Price
$1710
Updated
2021/12/16
Crysdot
Product number
CD31003614
Product name
Ca2+channelagonist1
Purity
98+%
Packaging
5mg
Price
$243
Updated
2021/12/16
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Ca2+ channel agonist 1 Chemical Properties,Usage,Production

Uses

Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction.

IC 50

CDK2: 3.34 μM (EC50); N-type calcium channel: 14.23 μM (EC50)

References

[1] Liang M, et al. Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist. ACS Med Chem Lett. 2012 Oct 1;3(12):985-990. DOI:10.1021/ml3002083

Ca2+ channel agonist 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Ca2+ channel agonist 1 Suppliers

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1402821-24-2, Ca2+ channel agonist 1Related Search:


  • Ca2+ channel agonist 1
  • 1-Butanol, 2-[[6-[(phenylmethyl)amino]-9-propyl-9H-purin-2-yl]amino]-, (2R)-
  • (R)-2-((6-(Benzylamino)-9-propyl-9H-purin-2-yl)amino)butan-1-ol
  • Ca2+ channels,Calcium Channel,Ca2+ channel agonist 1,Inhibitor,inhibit,Ca channels,Cyclin dependent kinase,CDK,Ca-2+ channel agonist 1
  • Ca2+ channel a onist 1
  • Ca2+ channel agonist 1, 10 mM in DMSO
  • 1402821-24-2