Amino-PEG5-alcohol
Uses- Product Name
- Amino-PEG5-alcohol
- CAS No.
- 34188-11-9
- Chemical Name
- Amino-PEG5-alcohol
- Synonyms
- NH2-PEG5-OH;NH2-PEG5-alcohol;HO-(CH2CH2O)5-NH2;Amino-PEG5-alcohol;14-amino-3,6,9,12-tetraoxatetradecanol;14-amino-3,6,9,12-tetraoxatetradecan-1-ol;3,6,9,12-Tetraoxatetradecan-1-ol, 14-amino-;2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethanol;H2N-PEG5-OH/3,6,9,12-Tetraoxatetradecan-1-ol, 14-amino-
- CBNumber
- CB33062321
- Molecular Formula
- C10H23NO5
- Formula Weight
- 237.29
- MOL File
- 34188-11-9.mol
Amino-PEG5-alcohol Property
- Boiling point:
- 346.3±32.0 °C(Predicted)
- Density
- 1.077±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- solubility
- Soluble in Water, DMSO, DMF, DCM
- pka
- 14.36±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
- InChI
- InChI=1S/C10H23NO5/c11-1-3-13-5-7-15-9-10-16-8-6-14-4-2-12/h12H,1-11H2
- InChIKey
- DEOUHEFHTMMUCM-UHFFFAOYSA-N
- SMILES
- C(O)COCCOCCOCCOCCN
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A621543
- Product name
- Amino-PEG5-alcohol
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FA159639
- Product name
- Amino-PEG5-alcohol
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA159639
- Product name
- Amino-PEG5-alcohol
- Packaging
- 1g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- AS103945
- Product name
- H2N-PEG5-OH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $361
- Updated
- 2021/12/16
- Product number
- 7296CZ
- Product name
- Amino-PEG5-alcohol
- Packaging
- 1g
- Price
- $397
- Updated
- 2021/12/16
Amino-PEG5-alcohol Chemical Properties,Usage,Production
Uses
Amino-PEG5-alcohol is a useful research chemical.
Description
Amino-PEG5-alcohol is an aqueousr soluble PEG linker with one amine and one hydroxyl group. The amine group is reactive with carboxylic acids, activated NHS esters etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Uses
NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
IC 50
PEGs; Non-cleavable Linker
References
[1] Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.
[2] Nianhe Han, et al. Derivatives of dolastatin 10 and uses thereof. WO2016192527A1.
Amino-PEG5-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
Amino-PEG5-alcohol Suppliers
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View Lastest Price from Amino-PEG5-alcohol manufacturers
- Product
- NH2-PEG5-OH 34188-11-9
- Price
- US $53.20/g
- Min. Order
- 10g
- Purity
- 98%
- Supply Ability
- 500kg
- Release date
- 2025-11-20
- Product
- 14-amino-3,6,9,12-tetraoxatetradecan-1-ol 34188-11-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- NH2-PEG5-OH 34188-11-9
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-06