Mal-Amido-PEG4-t-butyl ester

Product Name: Mal-Amido-PEG4-t-butyl ester
CAS No.: 1415800-35-9
Chemical Name: Mal-Amido-PEG4-t-butyl ester
Synonyms: Mal-NH-PEG4-OtBu;Mal-Amido-PEG4-Boc;MAL-NH-PEG4-CH2CH2COOTBU;Mal-Amido-PEG4-t-butyl ester;Mal-amiado-PEG4-t-buty1 ester;Mal-Amiado-PEG4-t-butyl ester;Maleimide-C2-Amido-PEG4-Carboxylic Acid tert-Butyl Ester;tert-Butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oate;tert-butyl 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate;N-(18,18-Dimethyl-15-oxo-3,6,9,12,17-pentaoxanonadecyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
CBNumber: CB33062523
Molecular Formula: C22H36N2O9
Formula Weight: 472.53
MOL File: 1415800-35-9.mol

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Mal-Amido-PEG4-t-butyl ester Property

solubility: DMSO : 200 mg/mL (423.25 mM; Need ultrasonic)
form: clear liquid
color: Colorless to Light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: M3267
Product name: Maleimide-C2-Amido-PEG4-Carboxylic Acid tert-Butyl Ester
Packaging: 250MG
Price: $640
Updated: 2025/07/31

TRC

Product number: M198150
Product name: Mal-Amido-PEG4-t-butylester
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-20998
Product name: Mal-Amido-PEG4-t-butylester
Purity: 98%
Packaging: 250mg
Price: $350
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: POL0002464
Product name: MAL-AMIDO-PEG4-TERTBUTYL ESTER
Purity: 95.00%
Packaging: 5MG
Price: $503.17
Updated: 2021/12/16

BroadPharm

Product number: BP-20998
Product name: Mal-Amido-PEG4-t-butylester
Purity: 98%
Packaging: 500mg
Price: $540
Updated: 2021/12/16

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Mal-Amido-PEG4-t-butyl ester Chemical Properties,Usage,Production

Description

Mal-Amido-PEG4-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-Amido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-Amido-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-Amido-PEG4-t-butyl ester Suppliers

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View Lastest Price from Mal-Amido-PEG4-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-amido-PEG4-COOtBu 1415800-35-9
Price: US $0.00/mg
Min. Order: 50mg
Purity: >98.00%
Supply Ability: 50mg
Release date: 2024-05-10

1415800-35-9, Mal-Amido-PEG4-t-butyl esterRelated Search:

Mal-Amido-PEG4-t-butyl ester

MAL-NH-PEG4-CH2CH2COOTBU

Mal-NH-PEG4-OtBu

Mal-Amido-PEG4-Boc

4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 1,1-dimethylethyl ester

Maleimide-C2-Amido-PEG4-Carboxylic Acid tert-Butyl Ester

N-(18,18-Dimethyl-15-oxo-3,6,9,12,17-pentaoxanonadec-1-yl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide

tert-butyl 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

Mal-Amiado-PEG4-t-butyl ester

Mal-amiado-PEG4-t-buty1 ester

tert-Butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oate

N-(18,18-Dimethyl-15-oxo-3,6,9,12,17-pentaoxanonadecyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide

1415800-35-9

C22H36N2O9

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