2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one

Product Name: 2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
CAS No.: 724711-21-1
Chemical Name: 2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
Synonyms: MK2-IN-3;MK2-IN-3, 10 mM in DMSO;MK2 Inhibitor III ，S6930;MK2 Inhibitor III (MK2-IN-3);2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one;2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one;2-[2-(quinolin-3-yl)pyridin-4-yl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one;4H-Pyrrolo[3,2-c]pyridin-4-one, 1,5,6,7-tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-;MAPK activated protein kinase 2,Mitogen-activated protein kinase activated protein kinase 2,inhibit,MK-2,Inhibitor,MAPKAPK2 (MK2),MK-5,MAPKAP kinase 2,ERK2,MAP kinase activated protein kinase 2,MK2IN3,MK-3,TNFα,MNK1,MK2 IN 3,MK-2-IN-3,MAPKAP-K2
CBNumber: CB33096984
Molecular Formula: C21H16N4O
Formula Weight: 340.38
MOL File: 724711-21-1.mol

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2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one Property

Boiling point:: 721.1±60.0 °C(Predicted)
Density: 1.318±0.06 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: DMSO : 62.5 mg/mL (183.62 mM)
form: Solid
pka: 13.80±0.20(Predicted)
color: Off-White to Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M424495
Product name: MK2InhibitorIII
Packaging: 25mg
Price: $785
Updated: 2021/12/16

Axon Medchem

Product number: Axon3440
Product name: MK2inhibitorIII
Purity: 99%
Packaging: 2x5mg
Price: $220
Updated: 2021/12/16

Ambeed

Product number: A950511
Product name: 2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one
Purity: 98+%
Packaging: 100mg
Price: $350
Updated: 2021/12/16

Ambeed

Product number: A950511
Product name: 2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one
Purity: 98+%
Packaging: 5mg
Price: $45
Updated: 2021/12/16

Ambeed

Product number: A950511
Product name: 2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one
Purity: 98+%
Packaging: 10mg
Price: $76
Updated: 2021/12/16

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2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one Chemical Properties,Usage,Production

Uses

MK2 Inhibitor III is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis.

in vivo

MK2-IN-3 (compound 16) (20 mg/kg; a single p.o. before LPS challenge) inhibits 20% TNFα production in rat LPS (rLPS) model^[1].

2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one Suppliers

China 50 United States 4 Global 54

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724711-21-1, 2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneRelated Search:

2-[2-(3-quinolyl)-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one

MK2-IN-3

2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one

MK2 Inhibitor III (MK2-IN-3)

MAPK activated protein kinase 2,Mitogen-activated protein kinase activated protein kinase 2,inhibit,MK-2,Inhibitor,MAPKAPK2 (MK2),MK-5,MAPKAP kinase 2,ERK2,MAP kinase activated protein kinase 2,MK2IN3,MK-3,TNFα,MNK1,MK2 IN 3,MK-2-IN-3,MAPKAP-K2

4H-Pyrrolo[3,2-c]pyridin-4-one, 1,5,6,7-tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-

2-[2-(quinolin-3-yl)pyridin-4-yl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one

MK2-IN-3, 10 mM in DMSO

MK2 Inhibitor III ，S6930

724711-21-1