ChemicalBook > CAS DataBase List > Madrasin

Madrasin

Product Name
Madrasin
CAS No.
374913-63-0
Chemical Name
Madrasin
Synonyms
CS-2251;Madrasin;DD00107587;DDD00107587;DDD-00107587;Madrasin >=98% (HPLC);DDD00107587;DD00107587;DDD-00107587;DDD-00107587,Madrasin,inhibit,Inhibitor,DDD 00107587;2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one;4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-
CBNumber
CB33123143
Molecular Formula
C16H17N5O2
Formula Weight
311.34
MOL File
374913-63-0.mol
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Madrasin Property

storage temp. 
2-8°C
solubility 
DMSO:1.5(Max Conc. mg/mL);4.82(Max Conc. mM)
form 
powder
color 
white to dark brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1409
Product name
Madrasin
Purity
≥98% (HPLC)
Packaging
5MG
Price
$115
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1409
Product name
Madrasin
Purity
≥98% (HPLC)
Packaging
25MG
Price
$451
Updated
2023/06/20
Cayman Chemical
Product number
20451
Product name
Madrasin
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
20451
Product name
Madrasin
Purity
≥95%
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
20451
Product name
Madrasin
Purity
≥95%
Packaging
10mg
Price
$169
Updated
2024/03/01
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Madrasin Chemical Properties,Usage,Production

Uses

Madrasin has been used as a spliceosome inhibitor to inhibit pre-mRNA processing in 3T3-L1 cells.

Definition

ChEBI: 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-1H-pyrimidin-4-one is a member of quinazolines.

Biochem/physiol Actions

Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. Madrasin stalls spliceosome assembly at the A complex.

Madrasin Preparation Products And Raw materials

Raw materials

Preparation Products

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Madrasin Suppliers

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View Lastest Price from Madrasin manufacturers

Career Henan Chemical Co
Product
Madrasin 374913-63-0
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

374913-63-0, MadrasinRelated Search:


  • Madrasin
  • DD00107587
  • DDD00107587
  • DDD-00107587
  • DDD00107587;DD00107587;DDD-00107587
  • CS-2251
  • 4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-
  • Madrasin >=98% (HPLC)
  • 2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one
  • DDD-00107587,Madrasin,inhibit,Inhibitor,DDD 00107587
  • 2-(7-Methoxy-4-methyl-quinazolin-2-ylamino)-5,6-dimethyl-3H-pyrimidin-4-one 2-[(7-Methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-4(1H)-pyrimidinone (9CI) 4(1H)-Pyrimidinone, 2-[(7-methoxy-4-methy
  • 374913-63-0
  • API