X-082

Product Name: X-082
CAS No.: 1013920-15-4
Chemical Name: X-082
Synonyms: X82;X-82;X 82;CM082;X-082;CM-082;CM 082;Vorolanib;X-82 (Vorolanib);Vorolanib, 10 mM in DMSO
CBNumber: CB33126649
Molecular Formula: C23H26FN5O3
Formula Weight: 439.48
MOL File: 1013920-15-4.mol

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X-082 Property

Boiling point:: 657.8±55.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 27 mg/mL (61.44 mM)
form: Solid
pka: 11.70±0.20(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0030517
Product name: Vorolanib
Purity: 99.80%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0030517
Product name: Vorolanib
Purity: 99.80%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0030517
Product name: Vorolanib
Purity: 99.80%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0030517
Product name: Vorolanib
Purity: 99.80%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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X-082 Chemical Properties,Usage,Production

Uses

Vorolanib is an oral anti-VEGFR/PDGFR/CSF1R tyrosine kinase inhibitor that can inhibit angiogenesis in vitro and in vivo.

in vivo

Vorolanib (CM082; 20 mg/kg; gavage; once every 2 days; 1 h before SKF 104864A; for 23 days) enhances the anti-tumor effect of SKF 104864A on xenografts of ABCG2-overexpressing cells^[1].
? Vorolanib (80 mg/kg; twice daily; for 21 days) has antitumor activity combined with ZD1839 (10 mg/kg; q.d; for 21 days) on H3255 tumor xenograft (female BALB/c nude mice aged five weeks)^[2].

X-082 Preparation Products And Raw materials

Raw materials

Preparation Products

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X-082 Suppliers

China 43 United States 3 Global 46

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai XingMo Biotechnology Co., Ltd.

Tel: +86 13524779951; 13524779951
Fax: QQ: 2075692521
Email: 2075692521@qq.com
Country: China
ProdList: 310
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 7218
Advantage: 58

Kaixin Chemical (Hong Kong) Limited

Tel: 010-88886666-01 13112345678
Fax: CDXH21@126.com
Email: loyson@tcypharm.com
Country: China
ProdList: 597
Advantage: 55

Hubei Yangxin Medical Technology Co., Ltd.

Tel: 15374522761
Fax: QQ:2853117752
Email: 3003392093@yongstandards.com
Country: China
ProdList: 10000
Advantage: 55

Shanghai Biopharmaleader Co., Ltd.

Tel: +86 18721201413
Fax: +86 (21) 5775-8967
Email: sales@biopharmaleader.com
Country: China
ProdList: 1720
Advantage: 58

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 5178
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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1013920-15-4, X-082Related Search:

4H-1-Benzopyran-4-one, 2-[2-chloro-4-(trifluoromethyl)phenyl]-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methyl-3-pyrrolidinyl]-, hydrochloride (1:1)

X-082

CM 082

CM082

CM-082

Vorolanib

X 82

X82

X-82

1H-Pyrrole-3-carboxamide, N-[(3S)-1-[(dimethylamino)carbonyl]-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-

VEGFR,PDGFR,X82,Vascular endothelial growth factor receptor,CM 082,transporter,angiogenesis,CM-082,X 82,Vorolanib,ATP-binding,tyrosine,ABC,Inhibitor,ABCG2,inhibit,Platelet-derived growth factor receptor,TKI,cassette,orally,kinase,HUVECs

X-82 (Vorolanib)

(S,Z)-N-(1-(Dimethylcarbamoyl)pyrrolidin-3-yl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

Vorolanib, 10 mM in DMSO

(S,Z)-N-[1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(5-fluoro-2-oxoindolin-3-ylidene)methyl]-2,4-dimethylpyrrole-3-carboxamide

1013920-15-4