ChemicalBook > CAS DataBase List > 7-Deaza-ddG

7-Deaza-ddG

Product Name
7-Deaza-ddG
CAS No.
111869-49-9
Chemical Name
7-Deaza-ddG
Synonyms
7-Deaza-ddG;2',3'-Dideoxy-7-Deazaguanosine;2-Amino-7-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one;2-Amino-7-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one;4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-1,7-dihydro-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]- (9CI)
CBNumber
CB33133227
Molecular Formula
C11H14N4O3
Formula Weight
250.25
MOL File
111869-49-9.mol
More
Less

7-Deaza-ddG Property

Melting point:
228 °C (decomp)
Density 
1.75±0.1 g/cm3(Predicted)
pka
11.29±0.20(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C11H14N4O3/c12-11-13-9-7(10(17)14-11)3-4-15(9)8-2-1-6(5-16)18-8/h3-4,6,8,16H,1-2,5H2,(H3,12,13,14,17)/t6-,8+/m0/s1
InChIKey
IRKZBFORRGBSAO-POYBYMJQSA-N
SMILES
C1(N)=NC(=O)C2C=CN([C@H]3CC[C@@H](CO)O3)C=2N1
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
D203253
Product name
7-Deaza-2'',3''-dideoxyguanosine
Packaging
2mg
Price
$60
Updated
2021/12/16
TRC
Product number
D203253
Product name
7-Deaza-2'',3''-dideoxyguanosine
Packaging
10mg
Price
$130
Updated
2021/12/16
AK Scientific
Product number
5947EM
Product name
2-Amino-7-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one
Packaging
5mg
Price
$137
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND06191
Product name
7-Deaza-2',3'-dideoxyguanosine
Packaging
50mg
Price
$215
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND06191
Product name
7-Deaza-2',3'-dideoxyguanosine
Packaging
100mg
Price
$425
Updated
2021/12/16
More
Less

7-Deaza-ddG Chemical Properties,Usage,Production

Uses

7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate, which can inhibit HIV-1 reverse transcriptase with a Ki of 25 nM[1].

IC 50

HIV-1

References

[1] Nicholas A Boyle, et al. Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase. J Med Chem. 2005 Apr 7;48(7):2695-700. DOI:10.1021/jm040101y

7-Deaza-ddG Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

7-Deaza-ddG Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
More
Less

View Lastest Price from 7-Deaza-ddG manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
7-Deaza-ddG 111869-49-9
Price
US $0.00-0.00/G
Min. Order
1G
Purity
97%
Supply Ability
2000
Release date
2025-05-30
Henan Aochuang Chemical Co.,Ltd.
Product
7-Deaza-ddG 111869-49-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26

111869-49-9, 7-Deaza-ddGRelated Search:


  • 7-Deaza-ddG
  • 2',3'-Dideoxy-7-Deazaguanosine
  • 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-1,7-dihydro-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]- (9CI)
  • 2-Amino-7-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
  • 2-Amino-7-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
  • 111869-49-9
  • 11869-49-9