SKL 2001
- Product Name
- SKL 2001
- CAS No.
- 909089-13-0
- Chemical Name
- SKL 2001
- Synonyms
- 2001;CS-2771;SKL 2001;SKL2001 free base;SKL-2001;SKL 2001;SKL2001;SKL-2001;SKL 2001;N-(3-(1H-imidazol-1-yl)propyl)-5-(furan-2-yl)isoxazole-3-carboxamide;3-Isoxazolecarboxamide, 5-(2-furanyl)-N-[3-(1H-imidazol-1-yl)propyl]-;Inhibitor,SKL-2001,Wnt,Beta catenin,SKL2001,SKL 2001,β-catenin,inhibit;5-(furan-2-yl)-N-[3-(1H-imidazol-1-yl)propyl]-1,2-oxazole-3-carboxamide
- CBNumber
- CB33146382
- Molecular Formula
- C14H14N4O3
- Formula Weight
- 286.29
- MOL File
- 909089-13-0.mol
SKL 2001 Property
- Boiling point:
- 595.7±50.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
- form
- A crystalline solid
- pka
- 13.36±0.46(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 26334
- Product name
- SKL2001
- Packaging
- 5mg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- 26334
- Product name
- SKL2001
- Packaging
- 10mg
- Price
- $92
- Updated
- 2024/03/01
- Product number
- 26334
- Product name
- SKL2001
- Packaging
- 25mg
- Price
- $216
- Updated
- 2024/03/01
- Product number
- 26334
- Product name
- SKL2001
- Packaging
- 100mg
- Price
- $665
- Updated
- 2024/03/01
- Product number
- CS-0020797
- Product name
- SKL2001
- Purity
- 99.54%
- Packaging
- 10mg
- Price
- $70
- Updated
- 2021/12/16
SKL 2001 Chemical Properties,Usage,Production
Description
SKL2001 is an activator of Wnt/β-catenin signaling. It increases β-catenin responsive transcription in a cell-based reporter assay in a concentration-dependent manner, increases β-catenin protein levels in HEK293 cells when used at concentrations of 10 and 30 μM, and disrupts the interaction between Axin and β-catenin. SKL2001 increases alkaline phosphatase (ALP) activity and mineralization in multipotent mesenchymal ST2 cells in a concentration-dependent manner, indicating increased osteoblastogenesis. SKL2001 (40 μM) reduces HCT116 and HT-29 spheroid growth and inhibits proliferation of HCT116 and HT-29 cells. It induces cell cycle arrest at the G0/G1 phase and increases E-cadherin and β-catenin protein levels in HCT116 cells when used at a concentration of 40 μM.
SKL 2001 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from SKL 2001 manufacturers
- Product
- SKL 2001;N-(3-(1H-imidazol-1-yl)propyl)-5-(furan-2-yl)isoxazole-3-carboxamide 909089-13-0
- Price
- US $1.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 95%~99%
- Supply Ability
- per week:100kg
- Release date
- 2019-09-05