ChemicalBook > CAS DataBase List > GNE-140 (racemate)
GNE-140 (racemate)
- Product Name
- GNE-140 (racemate)
- CAS No.
- 1802977-61-2
- Chemical Name
- GNE-140 (racemate)
- Synonyms
- GNE-140 (racemate);GNE-140 racemate (GNE 140 racemate;3-((2-chlorophenyl)thio)-6-(4-morpholinophenyl)-6-(thiophen-3-yl)piperidine-2,4-dione;2,4-Piperidinedione, 3-[(2-chlorophenyl)thio]-6-[4-(4-morpholinyl)phenyl]-6-(3-thienyl)-
- CBNumber
- CB33152079
- Molecular Formula
- C25H23ClN2O3S2
- Formula Weight
- 499.04
- MOL File
- 1802977-61-2.mol
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GNE-140 (racemate) Property
- Boiling point:
- 739.0±60.0 °C(Predicted)
- Density
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO : ≥ 34 mg/mL (68.13 mM)
- pka
- 9.61±0.70(Predicted)
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-5958
- Product name
- GNE-140(racemate)
- Purity
- 99.66%
- Packaging
- 1mg
- Price
- $120
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5958
- Product name
- GNE-140(racemate)
- Purity
- 99.66%
- Packaging
- 5mg
- Price
- $220
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- BG166816
- Product name
- GNE 140
- Packaging
- 10mg
- Price
- $225
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2927EF
- Product name
- GNE-140(racemate)
- Packaging
- 10mg
- Price
- $353
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5958
- Product name
- GNE-140(racemate)
- Purity
- 99.66%
- Packaging
- 10mg
- Price
- $370
- Updated
- 2021/12/16
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GNE-140 (racemate) Chemical Properties,Usage,Production
Description
GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potent lactate dehydrogenase A (LDHA) inhibitor
in vitro
Increased glucose consumption distinguishes cancer cells from normal cells and is known as the “Warburg effect” because of increased glycolysis. Lactate dehydrogenase A (LDHA) is a key glycolytic enzyme, a hallmark of aggressive cancers, and believed to be the major enzyme responsible for pyruvate-to-lactate conversion.
GNE-140 (racemate) Preparation Products And Raw materials
Raw materials
Preparation Products
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