Acetyl-Tau Peptide (273-284) amide
- Product Name
- Acetyl-Tau Peptide (273-284) amide
- CAS No.
- 1684399-52-7
- Chemical Name
- Acetyl-Tau Peptide (273-284) amide
- Synonyms
- Acetyl-Tau Peptide (273-284) amide;L-Leucinamide, N-acetylglycyl-L-lysyl-L-valyl-L-glutaminyl-L-isoleucyl-L-isoleucyl-L-asparaginyl-L-lysyl-L-lysyl-L-leucyl-L-α-aspartyl-
- CBNumber
- CB33158657
- Molecular Formula
- C64H116N18O17
- Formula Weight
- 1409.74
- MOL File
- 1684399-52-7.mol
Acetyl-Tau Peptide (273-284) amide Property
- Boiling point:
- 1733.8±65.0 °C(Predicted)
- Density
- 1.204±0.06 g/cm3(Predicted)
- pka
- 4.20±0.10(Predicted)
- Sequence
- Ac-Gly-Lys-Val-Gln-Ile-Ile-Asn-Lys-Lys-Leu-Asp-Leu-NH2
Acetyl-Tau Peptide (273-284) amide Chemical Properties,Usage,Production
Uses
Acetyl-Tau Peptide (273-284) amide is an acetylated Tau peptide fragment. Acetyl-Tau Peptide (273-284) amide limits the substantial aggregation of Ac-Aβ(25–35)-NH2 and can be used as an inhibitor of Ac-Aβ(25–35)-NH2. Acetyl-Tau Peptide (273-284) amide can be used as an experimental model to investigate the Aβ/Tau cross-interaction [1][2].
References
[1] Di Natale G, et al. Aβ and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease? Molecules. 2022 Aug 9;27(16):5066. DOI:10.3390/molecules27165066
[2] Do TD, et al. Interactions between amyloid-β and Tau fragments promote aberrant aggregates: implications for amyloid toxicity. J Phys Chem B. 2014 Sep 25;118(38):11220-30. DOI:10.1021/jp506258g
Acetyl-Tau Peptide (273-284) amide Preparation Products And Raw materials
Raw materials
Preparation Products
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