ChemicalBook > CAS DataBase List > GLPG0187

GLPG0187

Product Name: GLPG0187
CAS No.: 1320346-97-1
Chemical Name: GLPG0187
Synonyms: CS-2550;GLPG0187;GLPG 0187;GLPG-0187;GLPG0187, 10 mM in DMSO;inhibit,GLPG-0187,GLPG0187,GLPG 0187,Inhibitor,Integrin;GLPG0187, 98%, a broad spectrum integrin receptor antagonist with antitumor activity;L-Alanine, 3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-;(S)-3-(2,5-dimethyl-6-(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl)pyrimidin-4-ylamino)-2-(4-methoxyphenylsulfonamido)propanoic acid;(2S)-3-({2,5-dimethyl-6-[4-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl]pyrimidin-4-yl}amino)-2-(4-methoxybenzenesulfonamido)propanoic acid
CBNumber: CB33159669
Molecular Formula: C29H37N7O5S
Formula Weight: 595.71
MOL File: 1320346-97-1.mol

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GLPG0187 Property

Boiling point:: 894.7±75.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:8.0(Max Conc. mg/mL);13.43(Max Conc. mM)
form: A crystalline solid
pka: 2.86±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21792
Product name: GLPG0187
Purity: ≥98%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 21792
Product name: GLPG0187
Purity: ≥98%
Packaging: 5mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 21792
Product name: GLPG0187
Purity: ≥98%
Packaging: 10mg
Price: $286
Updated: 2024/03/01

Tocris

Product number: 7059
Product name: GLPG0187
Purity: ≥97%(HPLC)
Packaging: 10
Price: $215
Updated: 2021/12/16

TRC

Product number: G411800
Product name: GLPG-0187
Packaging: 5mg
Price: $330
Updated: 2021/12/16

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GLPG0187 Chemical Properties,Usage,Production

Uses

GLPG-0187 is an integrin receptor antagonist which displays anti-tumor activity.

in vivo

Blocking α_v-integrins by GLPG0187 markedly reduces their metastatic tumor growth. Bone tumor burden is significantly lower and the number of bone metastases/mouse is significantly inhibited. The progression of bone metastases and the formation of new bone metastases during the treatment period is significantly inhibited^[1].

storage

Store at -20°C

GLPG0187 Preparation Products And Raw materials

Raw materials

Preparation Products

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GLPG0187 Suppliers

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1320346-97-1, GLPG0187Related Search:

GLPG0187

GLPG0187, 98%, a broad spectrum integrin receptor antagonist with antitumor activity

(S)-3-(2,5-dimethyl-6-(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl)pyrimidin-4-ylamino)-2-(4-methoxyphenylsulfonamido)propanoic acid

CS-2550

GLPG 0187;GLPG-0187

L-Alanine, 3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-

inhibit,GLPG-0187,GLPG0187,GLPG 0187,Inhibitor,Integrin

(2S)-3-({2,5-dimethyl-6-[4-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl]pyrimidin-4-yl}amino)-2-(4-methoxybenzenesulfonamido)propanoic acid

GLPG0187, 10 mM in DMSO

1320346-97-1